Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1853522..1853662 Replicon chromosome
Accession NZ_CP055096
Organism Klebsiella pneumoniae strain SWHIN_108

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1853558..1853660 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1853522..1853662 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ85_RS08985 1848654..1850714 + 2061 WP_004151449.1 oligopeptidase B -
HUZ85_RS08990 1850718..1851377 - 660 WP_002911407.1 exodeoxyribonuclease X -
HUZ85_RS08995 1851456..1851686 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ85_RS09000 1851797..1852171 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ85_RS09005 1852175..1853044 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
HUZ85_RS09010 1853061..1853399 + 339 WP_002911404.1 YebY family protein -
- 1853522..1853662 - 141 - - Antitoxin
- 1853558..1853660 + 103 - - Toxin
HUZ85_RS09015 1853738..1854823 - 1086 WP_064190563.1 phage integrase Arm DNA-binding domain-containing protein -
HUZ85_RS09020 1854792..1855064 - 273 WP_074194905.1 excisionase -
HUZ85_RS09025 1855146..1855313 - 168 WP_102016074.1 hypothetical protein -
HUZ85_RS09030 1855352..1855612 - 261 WP_080882102.1 hypothetical protein -
HUZ85_RS09035 1855803..1855970 - 168 WP_074194906.1 DUF2737 family protein -
HUZ85_RS09040 1856019..1856303 - 285 WP_064190564.1 hypothetical protein -
HUZ85_RS09045 1856353..1856937 - 585 WP_064190565.1 hypothetical protein -
HUZ85_RS09050 1856934..1857614 - 681 WP_064190566.1 AAA family ATPase -
HUZ85_RS09055 1857596..1857763 - 168 WP_162779418.1 hypothetical protein -
HUZ85_RS09060 1858052..1858333 - 282 WP_074194907.1 hypothetical protein -
HUZ85_RS09065 1858320..1858484 - 165 WP_077259629.1 host cell division inhibitory peptide Kil -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1832923..1920407 87484


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161471 NZ_CP055096:1853558-1853660 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT161471 NZ_CP055096:c1853662-1853522 [Klebsiella pneumoniae]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References