Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1969215..1969486 Replicon chromosome
Accession NZ_CP055092
Organism Shigella flexneri strain SWHIN_110

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1969345..1969448 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1969215..1969486 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ87_RS09515 1965770..1966432 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUZ87_RS09520 1966456..1967112 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HUZ87_RS09525 1967214..1967444 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ87_RS09530 1967583..1967957 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HUZ87_RS09535 1967961..1968833 + 873 WP_046464082.1 copper homeostasis membrane protein CopD -
HUZ87_RS09540 1968846..1969187 + 342 WP_000976476.1 YebY family protein -
- 1969215..1969486 - 272 - - Antitoxin
- 1969345..1969448 + 104 - - Toxin
HUZ87_RS09545 1969583..1970239 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HUZ87_RS09550 1970240..1970431 - 192 WP_000457842.1 YebW family protein -
HUZ87_RS09555 1970536..1970772 - 237 WP_001295499.1 YebV family protein -
HUZ87_RS09560 1970890..1972329 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T161449 NZ_CP055092:1969345-1969448 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT161449 NZ_CP055092:c1969486-1969215 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References