Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2026914..2027058 | Replicon | chromosome |
| Accession | NZ_CP055087 | ||
| Organism | Klebsiella pneumoniae strain SWHIN_114 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2026950..2027052 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2026914..2027058 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ89_RS09845 (HUZ89_09850) | 2022044..2024104 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| HUZ89_RS09850 (HUZ89_09855) | 2024108..2024767 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HUZ89_RS09855 (HUZ89_09860) | 2024846..2025076 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HUZ89_RS09860 (HUZ89_09865) | 2025189..2025563 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| HUZ89_RS09865 (HUZ89_09870) | 2025567..2026436 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| HUZ89_RS09870 (HUZ89_09875) | 2026453..2026791 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2026914..2027058 | - | 145 | - | - | Antitoxin |
| - | 2026950..2027052 | + | 103 | - | - | Toxin |
| HUZ89_RS09875 (HUZ89_09880) | 2027185..2027466 | - | 282 | Protein_1930 | tyrosine-type recombinase/integrase | - |
| HUZ89_RS09880 (HUZ89_09885) | 2027543..2028022 | + | 480 | WP_032419797.1 | lysis protein | - |
| HUZ89_RS09885 | 2028477..2028672 | + | 196 | Protein_1932 | DNA polymerase V | - |
| HUZ89_RS09890 (HUZ89_09890) | 2028811..2030316 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| HUZ89_RS09895 (HUZ89_09895) | 2030566..2030994 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| HUZ89_RS09900 (HUZ89_09900) | 2031004..2031285 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T161406 NZ_CP055087:2026950-2027052 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT161406 NZ_CP055087:c2027058-2026914 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
