Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2036066..2036337 Replicon chromosome
Accession NZ_CP055075
Organism Shigella flexneri strain SWHIN_116

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2036196..2036299 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2036066..2036337 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ90_RS09800 2032621..2033283 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUZ90_RS09805 2033307..2033963 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
HUZ90_RS09810 2034065..2034295 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ90_RS09815 2034434..2034808 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HUZ90_RS09820 2034812..2035684 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
HUZ90_RS09825 2035697..2036038 + 342 WP_000976472.1 YebY family protein -
- 2036066..2036337 - 272 - - Antitoxin
- 2036196..2036299 + 104 - - Toxin
HUZ90_RS09830 2036434..2037090 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
HUZ90_RS09835 2037091..2037282 - 192 WP_001338167.1 YebW family protein -
HUZ90_RS09840 2037387..2037623 - 237 WP_001338166.1 YebV family protein -
HUZ90_RS09845 2037741..2039180 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T161376 NZ_CP055075:2036196-2036299 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT161376 NZ_CP055075:c2036337-2036066 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References