Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1922832..1922977 Replicon chromosome
Accession NZ_CP055066
Organism Klebsiella pneumoniae strain SWHE1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1922868..1922970 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1922832..1922977 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ64_RS09310 1917962..1920022 + 2061 WP_032419805.1 oligopeptidase B -
HUZ64_RS09315 1920026..1920685 - 660 WP_002911407.1 exodeoxyribonuclease X -
HUZ64_RS09320 1920764..1920994 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ64_RS09325 1921107..1921481 + 375 WP_020316569.1 CopC domain-containing protein YobA -
HUZ64_RS09330 1921485..1922354 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HUZ64_RS09335 1922371..1922709 + 339 WP_002911404.1 YebY family protein -
- 1922832..1922977 - 146 - - Antitoxin
- 1922868..1922970 + 103 - - Toxin
HUZ64_RS09340 1923345..1923488 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ64_RS09345 1923593..1924561 - 969 WP_014907334.1 VirK/YbjX family protein -
HUZ64_RS09350 1924718..1925371 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
HUZ64_RS09355 1925368..1925559 - 192 WP_002911395.1 YebW family protein -
HUZ64_RS09360 1925657..1925896 - 240 WP_002911393.1 YebV family protein -
HUZ64_RS09365 1926012..1927445 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161322 NZ_CP055066:1922868-1922970 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT161322 NZ_CP055066:c1922977-1922832 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References