Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1974222..1974367 Replicon chromosome
Accession NZ_CP055061
Organism Klebsiella pneumoniae strain SWHE3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1974258..1974360 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1974222..1974367 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ66_RS09560 (HUZ66_09550) 1969352..1971412 + 2061 WP_064145333.1 oligopeptidase B -
HUZ66_RS09565 (HUZ66_09555) 1971416..1972075 - 660 WP_002911407.1 exodeoxyribonuclease X -
HUZ66_RS09570 (HUZ66_09560) 1972154..1972384 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ66_RS09575 (HUZ66_09565) 1972497..1972871 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ66_RS09580 (HUZ66_09570) 1972875..1973744 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HUZ66_RS09585 (HUZ66_09575) 1973761..1974099 + 339 WP_002911404.1 YebY family protein -
- 1974222..1974367 - 146 - - Antitoxin
- 1974258..1974360 + 103 - - Toxin
HUZ66_RS09590 (HUZ66_09580) 1974736..1974879 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ66_RS09595 (HUZ66_09585) 1974984..1975952 - 969 WP_004151446.1 VirK/YbjX family protein -
HUZ66_RS09600 (HUZ66_09590) 1976109..1976762 + 654 WP_064145335.1 protein-serine/threonine phosphatase -
HUZ66_RS09605 (HUZ66_09595) 1976759..1976950 - 192 WP_002911395.1 YebW family protein -
HUZ66_RS09610 (HUZ66_09600) 1977048..1977287 - 240 WP_002911393.1 YebV family protein -
HUZ66_RS09615 (HUZ66_09605) 1977403..1978836 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161302 NZ_CP055061:1974258-1974360 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT161302 NZ_CP055061:c1974367-1974222 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References