Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2706133..2706404 Replicon chromosome
Accession NZ_CP055055
Organism Shigella dysenteriae strain SWHEFF_49

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2706171..2706274 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2706133..2706404 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ68_RS12930 2703290..2704729 + 1440 WP_033814685.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HUZ68_RS12935 2704847..2705083 + 237 WP_001295499.1 YebV family protein -
HUZ68_RS12940 2705188..2705379 + 192 WP_001296140.1 YebW family protein -
HUZ68_RS12945 2705383..2706036 - 654 WP_239593892.1 protein-serine/threonine phosphatase -
- 2706133..2706404 + 272 - - Antitoxin
- 2706171..2706274 - 104 - - Toxin
HUZ68_RS12950 2706432..2706773 - 342 WP_000976483.1 YebY family protein -
HUZ68_RS12955 2706785..2707657 - 873 WP_033814654.1 copper homeostasis membrane protein CopD -
HUZ68_RS12960 2707661..2708035 - 375 WP_000168747.1 CopC domain-containing protein YobA -
HUZ68_RS12965 2708174..2708404 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ68_RS12970 2708506..2709162 + 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
HUZ68_RS12975 2709186..2709848 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T161256 NZ_CP055055:c2706274-2706171 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT161256 NZ_CP055055:2706133-2706404 [Shigella dysenteriae]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTAAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References