Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 291585..291856 Replicon chromosome
Accession NZ_CP055048
Organism Escherichia coli strain SWHEFF_58

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 291715..291818 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 291585..291856 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ70_RS01460 288140..288802 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUZ70_RS01465 288826..289482 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
HUZ70_RS01470 289584..289814 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ70_RS01475 289953..290327 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HUZ70_RS01480 290331..291203 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
HUZ70_RS01485 291216..291557 + 342 WP_000976472.1 YebY family protein -
- 291585..291856 - 272 - - Antitoxin
- 291715..291818 + 104 - - Toxin
HUZ70_RS01490 291953..292609 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
HUZ70_RS01495 292610..292801 - 192 WP_001296140.1 YebW family protein -
HUZ70_RS01500 292906..293142 - 237 WP_001295499.1 YebV family protein -
HUZ70_RS01505 293260..294699 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 282412..307696 25284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T161195 NZ_CP055048:291715-291818 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT161195 NZ_CP055048:c291856-291585 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References