Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ataRT/ElaA-DUF1778 |
Location | 209161..209912 | Replicon | plasmid unnamed1 |
Accession | NZ_CP055034 | ||
Organism | Klebsiella pneumoniae strain SWHEFF_62 |
Toxin (Protein)
Gene name | ataT | Uniprot ID | - |
Locus tag | HUZ73_RS26700 | Protein ID | WP_072046196.1 |
Coordinates | 209161..209643 (-) | Length | 161 a.a. |
Antitoxin (Protein)
Gene name | ataR | Uniprot ID | A0A071LPN3 |
Locus tag | HUZ73_RS26705 | Protein ID | WP_004902250.1 |
Coordinates | 209634..209912 (-) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HUZ73_RS26685 (HUZ73_26590) | 204469..205992 | - | 1524 | WP_239594580.1 | EAL domain-containing protein | - |
HUZ73_RS26690 (HUZ73_26595) | 206372..207340 | + | 969 | WP_239594581.1 | IS5-like element IS903B family transposase | - |
HUZ73_RS26695 (HUZ73_26600) | 207586..208125 | - | 540 | WP_135720529.1 | hypothetical protein | - |
HUZ73_RS26700 (HUZ73_26605) | 209161..209643 | - | 483 | WP_072046196.1 | GNAT family N-acetyltransferase | Toxin |
HUZ73_RS26705 (HUZ73_26610) | 209634..209912 | - | 279 | WP_004902250.1 | DUF1778 domain-containing protein | Antitoxin |
HUZ73_RS26710 (HUZ73_26615) | 210031..210243 | - | 213 | WP_004902255.1 | hypothetical protein | - |
HUZ73_RS26715 (HUZ73_26620) | 210351..210692 | - | 342 | WP_135720527.1 | hypothetical protein | - |
HUZ73_RS26940 | 211278..211424 | - | 147 | Protein_228 | DUF2235 domain-containing protein | - |
HUZ73_RS26725 | 211459..211569 | + | 111 | Protein_229 | glutathione ABC transporter permease GsiC | - |
HUZ73_RS26730 (HUZ73_26630) | 211653..213323 | - | 1671 | WP_032413257.1 | AMP-binding protein | - |
HUZ73_RS26735 (HUZ73_26635) | 213304..214569 | - | 1266 | WP_048281137.1 | MSMEG_0569 family flavin-dependent oxidoreductase | - |
HUZ73_RS26740 (HUZ73_26640) | 214587..214877 | - | 291 | WP_032413253.1 | MSMEG_0570 family nitrogen starvation response protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | qnrS1 / blaLAP-2 / aph(6)-Id / floR / sul2 / aph(4)-Ia / aac(3)-IVa / aph(3')-Ia / aadA2 / dfrA12 / tet(A) | iutA / iucD / iucC / iucB / iucA / pla | 1..242129 | 242129 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 161 a.a. Molecular weight: 17678.45 Da Isoelectric Point: 8.9130
>T161136 WP_072046196.1 NZ_CP055034:c209643-209161 [Klebsiella pneumoniae]
MGMRAPESLTAEHNIAEFCCQEPALNEWLKKKALRNHSTGISRVYVVCAENTNRVIGYYCLSSGSVHRNTVPGAYRRNAP
DVIPVIVLGRLAIDQAWSGNGLGAALLKDAIYRTQNIAFQVGVRALAVHALNEEVKCFYTRFGFEPSIVNTLTLLFPIKV
MGMRAPESLTAEHNIAEFCCQEPALNEWLKKKALRNHSTGISRVYVVCAENTNRVIGYYCLSSGSVHRNTVPGAYRRNAP
DVIPVIVLGRLAIDQAWSGNGLGAALLKDAIYRTQNIAFQVGVRALAVHALNEEVKCFYTRFGFEPSIVNTLTLLFPIKV
Download Length: 483 bp
>T161136 NZ_CP071063:469519-469803 [Enterobacter mori]
ATGACTTATGAACTGGCGTTTGATCCGAGGGCGTTAAAGGAGTGGAGCAAGCTGGGGGAGACTGTAAAAGACCATTTTAA
GAAGAAACTTGCGGATGTGTTGGTGAACCCAAGGGTCGAATCGGCCCGCCTGCATGGTCTACCGGATTGCTACAAAATAA
AACTCAGATCGCAGGGTTATCGTTTGGTCTATCAGGTTCAGGACAATGTTGTAACGGTATTTGTTATCGCTATCGGTAAG
AGAGAGAAATCAGCCGTTTATCATGATGCAAACAAACGGCTTTAG
ATGACTTATGAACTGGCGTTTGATCCGAGGGCGTTAAAGGAGTGGAGCAAGCTGGGGGAGACTGTAAAAGACCATTTTAA
GAAGAAACTTGCGGATGTGTTGGTGAACCCAAGGGTCGAATCGGCCCGCCTGCATGGTCTACCGGATTGCTACAAAATAA
AACTCAGATCGCAGGGTTATCGTTTGGTCTATCAGGTTCAGGACAATGTTGTAACGGTATTTGTTATCGCTATCGGTAAG
AGAGAGAAATCAGCCGTTTATCATGATGCAAACAAACGGCTTTAG
Antitoxin
Download Length: 93 a.a. Molecular weight: 10704.23 Da Isoelectric Point: 4.5271
>AT161136 WP_004902250.1 NZ_CP055034:c209912-209634 [Klebsiella pneumoniae]
MKPDVREAPINIRAKTSQRDLIDMAASLVSKSRTDFMLEVACREAQDILLDQRLFLLNDNQFEAFIEELDAPITPERQAR
IDNLMNRKSPWE
MKPDVREAPINIRAKTSQRDLIDMAASLVSKSRTDFMLEVACREAQDILLDQRLFLLNDNQFEAFIEELDAPITPERQAR
IDNLMNRKSPWE
Download Length: 279 bp
>AT161136 NZ_CP071063:469287-469529 [Enterobacter mori]
ATGGCCACGCTTAACGTCCGTCTGGATGACAAACTCAAAAACGAGGCTTACGCCGTGCTGGAAAAACTCAACATCACCCC
TACGGAAGCGGTACGATTACTGTTTCAGTACGTAGCTGAAACAGGACGCATGCCCGTGAAAACGGTCACGATTAGTGACA
GCGAAGATGCGCTGATACAGACGGTCCGGGAGCGGCTGGCTAATCCGCAAAAGGGAATTAAGGTTAGTCTGGATGACTTA
TGA
ATGGCCACGCTTAACGTCCGTCTGGATGACAAACTCAAAAACGAGGCTTACGCCGTGCTGGAAAAACTCAACATCACCCC
TACGGAAGCGGTACGATTACTGTTTCAGTACGTAGCTGAAACAGGACGCATGCCCGTGAAAACGGTCACGATTAGTGACA
GCGAAGATGCGCTGATACAGACGGTCCGGGAGCGGCTGGCTAATCCGCAAAAGGGAATTAAGGTTAGTCTGGATGACTTA
TGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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