Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1810328..1810473 Replicon chromosome
Accession NZ_CP055033
Organism Klebsiella pneumoniae strain SWHEFF_62

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1810364..1810466 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1810328..1810473 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ73_RS08775 1805458..1807518 + 2061 WP_004151449.1 oligopeptidase B -
HUZ73_RS08780 1807522..1808181 - 660 WP_002911407.1 exodeoxyribonuclease X -
HUZ73_RS08785 1808260..1808490 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ73_RS08790 1808603..1808977 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ73_RS08795 1808981..1809850 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
HUZ73_RS08800 1809867..1810205 + 339 WP_016529031.1 YebY family protein -
- 1810328..1810473 - 146 - - Antitoxin
- 1810364..1810466 + 103 - - Toxin
HUZ73_RS08805 1810842..1810985 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ73_RS08810 1811090..1812058 - 969 WP_004151446.1 VirK/YbjX family protein -
HUZ73_RS08815 1812215..1812868 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
HUZ73_RS08820 1812865..1813056 - 192 WP_002911395.1 YebW family protein -
HUZ73_RS08825 1813154..1813393 - 240 WP_002911393.1 YebV family protein -
HUZ73_RS08830 1813509..1814942 - 1434 WP_048292090.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161119 NZ_CP055033:1810364-1810466 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT161119 NZ_CP055033:c1810473-1810328 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References