Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2024548..2024819 | Replicon | chromosome |
| Accession | NZ_CP055030 | ||
| Organism | Shigella flexneri strain SWHEFF_64 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2024678..2024781 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2024548..2024819 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ74_RS09735 | 2021103..2021765 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| HUZ74_RS09740 | 2021789..2022445 | - | 657 | WP_000011657.1 | carbon-nitrogen hydrolase family protein YobB | - |
| HUZ74_RS09745 | 2022547..2022777 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HUZ74_RS09750 | 2022916..2023290 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| HUZ74_RS09755 | 2023294..2024166 | + | 873 | WP_000879298.1 | copper homeostasis membrane protein CopD | - |
| HUZ74_RS09760 | 2024179..2024520 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 2024548..2024819 | - | 272 | - | - | Antitoxin |
| - | 2024678..2024781 | + | 104 | - | - | Toxin |
| HUZ74_RS09765 | 2024916..2025572 | + | 657 | WP_000812733.1 | protein-serine/threonine phosphatase | - |
| HUZ74_RS09770 | 2025573..2025764 | - | 192 | WP_001338167.1 | YebW family protein | - |
| HUZ74_RS09775 | 2025869..2026105 | - | 237 | WP_001338166.1 | YebV family protein | - |
| HUZ74_RS09780 | 2026223..2027662 | - | 1440 | WP_024238487.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T161100 NZ_CP055030:2024678-2024781 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT161100 NZ_CP055030:c2024819-2024548 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
