Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 850593..850864 Replicon chromosome
Accession NZ_CP055015
Organism Shigella flexneri strain SWHEFF_71

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 850631..850734 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 850593..850864 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ78_RS04305 847750..849189 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HUZ78_RS04310 849307..849543 + 237 WP_001295499.1 YebV family protein -
HUZ78_RS04315 849648..849839 + 192 WP_001296140.1 YebW family protein -
HUZ78_RS04320 849840..850496 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 850593..850864 + 272 - - Antitoxin
- 850631..850734 - 104 - - Toxin
HUZ78_RS04325 850892..851233 - 342 WP_000976492.1 YebY family protein -
HUZ78_RS04330 851246..852118 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HUZ78_RS04335 852122..852496 - 375 WP_000204699.1 CopC domain-containing protein YobA -
HUZ78_RS04340 852635..852865 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ78_RS04345 852967..853623 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HUZ78_RS04350 853647..854309 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T160983 NZ_CP055015:c850734-850631 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT160983 NZ_CP055015:850593-850864 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ATGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References