Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yfjZ-ypjF/CbtA-CbeA |
Location | 4266999..4267690 | Replicon | chromosome |
Accession | NZ_CP055005 | ||
Organism | Klebsiella pneumoniae strain STIN_77 |
Toxin (Protein)
Gene name | ypjF | Uniprot ID | A0A2A3UTQ9 |
Locus tag | HUZ53_RS21025 | Protein ID | WP_001094399.1 |
Coordinates | 4267322..4267690 (+) | Length | 123 a.a. |
Antitoxin (Protein)
Gene name | yfjZ | Uniprot ID | - |
Locus tag | HUZ53_RS21020 | Protein ID | WP_001405555.1 |
Coordinates | 4266999..4267301 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HUZ53_RS20990 (HUZ53_20955) | 4263730..4263963 | + | 234 | WP_001117568.1 | DUF905 family protein | - |
HUZ53_RS20995 (HUZ53_20960) | 4264054..4264872 | + | 819 | WP_097586124.1 | DUF932 domain-containing protein | - |
HUZ53_RS21000 (HUZ53_20965) | 4264963..4265448 | + | 486 | WP_000214318.1 | antirestriction protein | - |
HUZ53_RS21005 (HUZ53_20970) | 4265463..4265939 | + | 477 | WP_001186742.1 | RadC family protein | - |
HUZ53_RS21010 (HUZ53_20975) | 4266008..4266229 | + | 222 | WP_000692315.1 | DUF987 domain-containing protein | - |
HUZ53_RS21015 (HUZ53_20980) | 4266248..4266892 | + | 645 | WP_000086755.1 | hypothetical protein | - |
HUZ53_RS21020 (HUZ53_20985) | 4266999..4267301 | + | 303 | WP_001405555.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
HUZ53_RS21025 (HUZ53_20990) | 4267322..4267690 | + | 369 | WP_001094399.1 | TA system toxin CbtA family protein | Toxin |
HUZ53_RS21030 (HUZ53_20995) | 4267779..4268456 | + | 678 | WP_001682408.1 | IS66-like element accessory protein TnpA | - |
HUZ53_RS21035 (HUZ53_21000) | 4268456..4268803 | + | 348 | WP_000624622.1 | IS66 family insertion sequence element accessory protein TnpB | - |
HUZ53_RS21040 (HUZ53_21005) | 4268823..4270394 | + | 1572 | WP_000381395.1 | IS66-like element ISCro1 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 4252230..4268456 | 16226 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 123 a.a. Molecular weight: 13568.73 Da Isoelectric Point: 7.7465
>T160948 WP_001094399.1 NZ_CP055005:4267322-4267690 [Klebsiella pneumoniae]
MNTLPATISPAAKPCPSPVAVWQMLLTRLLEQHYGLMLSDTPFSDETVIKEHIDAGITLANAVNFLVEKYELVRIDRNGF
TSQVQAPYLTATDILQARKACGLMSRCSYRDVSNIVLSRSRL
MNTLPATISPAAKPCPSPVAVWQMLLTRLLEQHYGLMLSDTPFSDETVIKEHIDAGITLANAVNFLVEKYELVRIDRNGF
TSQVQAPYLTATDILQARKACGLMSRCSYRDVSNIVLSRSRL
Download Length: 369 bp
>T160948 NZ_CP070976:c2259137-2258961 [Bacillus halotolerans]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGATAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTACACGTAAGCGACTCCGTAGCAAGAGGCAACGCA
AACGTATACGCAGATGA
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGATAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTACACGTAAGCGACTCCGTAGCAAGAGGCAACGCA
AACGTATACGCAGATGA
Antitoxin
Download Length: 101 a.a. Molecular weight: 11132.66 Da Isoelectric Point: 6.0454
>AT160948 WP_001405555.1 NZ_CP055005:4266999-4267301 [Klebsiella pneumoniae]
VGLPYTVTPCSGTRLVQEGNRLYYLADRASITGKFSDAESLKLDVVFPHFISQMESMLTTGEMNPRHAHCFTLYHNGFTC
EADTLGSCGYVYIAIYPTQL
VGLPYTVTPCSGTRLVQEGNRLYYLADRASITGKFSDAESLKLDVVFPHFISQMESMLTTGEMNPRHAHCFTLYHNGFTC
EADTLGSCGYVYIAIYPTQL
Download Length: 303 bp
>AT160948 NZ_CP070976:2259078-2259178 [Bacillus halotolerans]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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