Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1938833..1938977 Replicon chromosome
Accession NZ_CP055005
Organism Klebsiella pneumoniae strain STIN_77

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1938869..1938971 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1938833..1938977 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ53_RS09370 (HUZ53_09370) 1933963..1936023 + 2061 WP_004151449.1 oligopeptidase B -
HUZ53_RS09375 (HUZ53_09375) 1936027..1936686 - 660 WP_002911407.1 exodeoxyribonuclease X -
HUZ53_RS09380 (HUZ53_09380) 1936765..1936995 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ53_RS09385 (HUZ53_09385) 1937108..1937482 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ53_RS09390 (HUZ53_09390) 1937486..1938355 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
HUZ53_RS09395 (HUZ53_09395) 1938372..1938710 + 339 WP_002911404.1 YebY family protein -
- 1938833..1938977 - 145 - - Antitoxin
- 1938869..1938971 + 103 - - Toxin
HUZ53_RS09400 (HUZ53_09400) 1939104..1939385 - 282 Protein_1836 tyrosine-type recombinase/integrase -
HUZ53_RS09405 (HUZ53_09405) 1939462..1939941 + 480 WP_032419797.1 lysis protein -
HUZ53_RS09410 1940396..1940591 + 196 Protein_1838 DNA polymerase V -
HUZ53_RS09415 (HUZ53_09410) 1940730..1942235 + 1506 WP_020956680.1 hypothetical protein -
HUZ53_RS09420 (HUZ53_09415) 1942485..1942913 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
HUZ53_RS09425 (HUZ53_09420) 1942923..1943204 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T160938 NZ_CP055005:1938869-1938971 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT160938 NZ_CP055005:c1938977-1938833 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References