Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1993722..1993993 Replicon chromosome
Accession NZ_CP055000
Organism Shigella flexneri strain STIN_80

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1993852..1993955 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1993722..1993993 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ55_RS09655 1990277..1990939 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUZ55_RS09660 1990963..1991619 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
HUZ55_RS09665 1991721..1991951 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ55_RS09670 1992090..1992464 + 375 WP_000255065.1 CopC domain-containing protein YobA -
HUZ55_RS09675 1992468..1993340 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
HUZ55_RS09680 1993353..1993694 + 342 WP_000976472.1 YebY family protein -
- 1993722..1993993 - 272 - - Antitoxin
- 1993852..1993955 + 104 - - Toxin
HUZ55_RS09685 1994090..1994746 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
HUZ55_RS09690 1994747..1994938 - 192 WP_001338167.1 YebW family protein -
HUZ55_RS09695 1995043..1995279 - 237 WP_001338166.1 YebV family protein -
HUZ55_RS09700 1995397..1996836 - 1440 WP_001338165.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1985535..2009831 24296


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T160887 NZ_CP055000:1993852-1993955 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT160887 NZ_CP055000:c1993993-1993722 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References