Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2021305..2021576 | Replicon | chromosome |
| Accession | NZ_CP054992 | ||
| Organism | Shigella flexneri strain STIN_87 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2021435..2021538 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2021305..2021576 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ57_RS09840 | 2017860..2018522 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| HUZ57_RS09845 | 2018546..2019202 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| HUZ57_RS09850 | 2019304..2019534 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HUZ57_RS09855 | 2019673..2020047 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| HUZ57_RS09860 | 2020051..2020923 | + | 873 | WP_039268383.1 | copper homeostasis membrane protein CopD | - |
| HUZ57_RS09865 | 2020936..2021277 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2021305..2021576 | - | 272 | - | - | Antitoxin |
| - | 2021435..2021538 | + | 104 | - | - | Toxin |
| HUZ57_RS09870 | 2021673..2022329 | + | 657 | WP_000812724.1 | protein-serine/threonine phosphatase | - |
| HUZ57_RS09875 | 2022330..2022521 | - | 192 | WP_000457842.1 | YebW family protein | - |
| HUZ57_RS09880 | 2022626..2022862 | - | 237 | WP_001295499.1 | YebV family protein | - |
| HUZ57_RS09885 | 2022980..2024419 | - | 1440 | WP_001352260.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T160841 NZ_CP054992:2021435-2021538 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT160841 NZ_CP054992:c2021576-2021305 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
