Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2048767..2049038 Replicon chromosome
Accession NZ_CP054977
Organism Shigella flexneri strain STIN_92

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2048897..2049000 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2048767..2049038 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ60_RS09900 2045322..2045984 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUZ60_RS09905 2046008..2046664 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HUZ60_RS09910 2046766..2046996 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ60_RS09915 2047135..2047509 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HUZ60_RS09920 2047513..2048385 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HUZ60_RS09925 2048398..2048739 + 342 WP_000976476.1 YebY family protein -
- 2048767..2049038 - 272 - - Antitoxin
- 2048897..2049000 + 104 - - Toxin
HUZ60_RS09930 2049135..2049791 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HUZ60_RS09935 2049792..2049983 - 192 WP_000457842.1 YebW family protein -
HUZ60_RS09940 2050088..2050324 - 237 WP_001295499.1 YebV family protein -
HUZ60_RS09945 2050442..2051881 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T160780 NZ_CP054977:2048897-2049000 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT160780 NZ_CP054977:c2049038-2048767 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References