Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1853808..1853953 Replicon chromosome
Accession NZ_CP054972
Organism Klebsiella pneumoniae strain STIN_93

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1853844..1853946 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1853808..1853953 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ61_RS09005 1848938..1850998 + 2061 WP_004151449.1 oligopeptidase B -
HUZ61_RS09010 1851002..1851661 - 660 WP_021440386.1 exodeoxyribonuclease X -
HUZ61_RS09015 1851740..1851970 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ61_RS09020 1852083..1852457 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ61_RS09025 1852461..1853330 + 870 WP_239593572.1 copper homeostasis membrane protein CopD -
HUZ61_RS09030 1853347..1853685 + 339 WP_002911404.1 YebY family protein -
- 1853808..1853953 - 146 - - Antitoxin
- 1853844..1853946 + 103 - - Toxin
HUZ61_RS09035 1854322..1854465 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ61_RS09040 1854570..1855538 - 969 WP_004151446.1 VirK/YbjX family protein -
HUZ61_RS09045 1855695..1856348 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HUZ61_RS09050 1856345..1856536 - 192 WP_002911395.1 YebW family protein -
HUZ61_RS09055 1856634..1856873 - 240 WP_002911393.1 YebV family protein -
HUZ61_RS09060 1856989..1858422 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T160754 NZ_CP054972:1853844-1853946 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT160754 NZ_CP054972:c1853953-1853808 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References