Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2789233..2789903 Replicon chromosome
Accession NZ_CP054923
Organism Verrucosispora sp. NA02020

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HUT12_RS12245 Protein ID WP_131053375.1
Coordinates 2789478..2789903 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HUT12_RS12240 Protein ID WP_131053372.1
Coordinates 2789233..2789478 (+) Length 82 a.a.

Genomic Context

HUT12_RS12225HUT12_RS12235HUT12_RS12240HUT12_RS12245HUT12_RS12230
Location: 2784751..2785692 (942 bp)
Type: Others
Protein ID: WP_131055301.1
Location: 2788804..2789112 (309 bp)
Type: Others
Protein ID: WP_131053373.1
Location: 2789233..2789478 (246 bp)
Type: Antitoxin
Protein ID: WP_131053372.1
Location: 2789478..2789903 (426 bp)
Type: Toxin
Protein ID: WP_131053375.1
Location: 2785759..2788494 (2736 bp)
Type: Others
Protein ID: WP_176093434.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HUT12_RS122252784751..2785692+942WP_131055301.1hypothetical protein-
HUT12_RS122302785759..2788494-2736WP_176093434.1LuxR family transcriptional regulator-
HUT12_RS122352788804..2789112+309WP_131053373.1N-acetyltransferase-
HUT12_RS122402789233..2789478+246WP_131053372.1Arc family DNA-binding proteinAntitoxin
HUT12_RS122452789478..2789903+426WP_131053375.1type II toxin-antitoxin system VapC family toxinToxin

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-125)

Antitoxin

Arc-like DNA binding domain

(13-48)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15188.26 Da        Isoelectric Point: 5.7035

>T160632 WP_131053375.1 NZ_CP054923:2789478-2789903 [Verrucosispora sp. NA02020]
MIVLDTNVVSELMRAEPAPVVLAWIQRNSRAGLYTTAITVAEIRYGIARLPAGQRRESLHQAANEIFAAFPRQVLPFDLG
AASAYADVVAGRDRLGHPIDGFDAQIAAICRAQAATLATRNTKDFTDTGIGVVDPWQEPSA

Download         Length: 426 bp

>T160632 NZ_CP070598:385961-386308 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATGCCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTGTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGTGGGCAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8900.07 Da        Isoelectric Point: 5.8508

>AT160632 WP_131053372.1 NZ_CP054923:2789233-2789478 [Verrucosispora sp. NA02020]
MAALSIRDLDDAVREKLRRRAAQHGRSMEAEIRDILTRAVAEDAPVNDLFGALTDRFARLGGVELELPSRSTSPRAASLP
E

Download         Length: 246 bp

>AT160632 NZ_CP070598:386308-386607 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References