Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3122259..3122493 | Replicon | chromosome |
| Accession | NZ_CP054913 | ||
| Organism | Shigella flexneri strain FDAARGOS_691 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3122260..3122363 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3122259..3122493 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FOB99_RS15565 | 3117705..3118172 | - | 468 | Protein_3025 | DNA-binding transcriptional regulator PgrR | - |
| FOB99_RS15570 | 3118236..3118546 | + | 311 | Protein_3026 | transposase | - |
| FOB99_RS15575 | 3118589..3119784 | - | 1196 | Protein_3027 | IS3 family transposase | - |
| FOB99_RS15580 | 3119839..3120687 | + | 849 | Protein_3028 | IS3-like element IS600 family transposase | - |
| FOB99_RS15585 | 3120804..3121085 | + | 282 | WP_005127484.1 | excisionase | - |
| FOB99_RS15590 | 3121051..3121443 | + | 393 | WP_001189099.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| FOB99_RS15595 | 3121762..3122128 | + | 367 | Protein_3031 | tyrosine-type recombinase/integrase | - |
| - | 3122259..3122493 | + | 235 | - | - | Antitoxin |
| - | 3122260..3122363 | - | 104 | - | - | Toxin |
| FOB99_RS15600 | 3122521..3122862 | - | 342 | WP_000976476.1 | YebY family protein | - |
| FOB99_RS15605 | 3122875..3123747 | - | 873 | Protein_3033 | copper homeostasis membrane protein CopD | - |
| FOB99_RS15610 | 3123751..3124125 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| FOB99_RS15615 | 3124264..3124494 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| FOB99_RS15620 | 3124596..3125252 | + | 657 | Protein_3036 | carbon-nitrogen hydrolase family protein | - |
| FOB99_RS15625 | 3125276..3125938 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 3117705..3147844 | 30139 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T160616 NZ_CP054913:c3122363-3122260 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT160616 NZ_CP054913:3122259-3122493 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
