160597

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 187535..188270 Replicon chromosome
Accession NZ_CP054912
Organism Pantoea ananatis strain FDAARGOS_680

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FOB88_RS03745 Protein ID WP_176017547.1
Coordinates 187535..187927 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FOB88_RS03750 Protein ID WP_014605595.1
Coordinates 187917..188270 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB88_RS03725 182835..184007 - 1173 WP_013026120.1 FMNH2-dependent alkanesulfonate monooxygenase -
FOB88_RS03730 184109..184261 - 153 WP_176017546.1 hypothetical protein -
FOB88_RS03735 184282..186168 + 1887 WP_072138116.1 aliphatic sulfonate ABC transporter substrate-binding protein -
FOB88_RS03740 186263..187210 + 948 WP_105082159.1 sulfonate ABC transporter substrate-binding protein -
FOB88_RS03745 187535..187927 + 393 WP_176017547.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOB88_RS03750 187917..188270 + 354 WP_014605595.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FOB88_RS03770 188978..190156 - 1179 WP_176017548.1 tyrosine-type recombinase/integrase -
FOB88_RS03775 190114..190320 - 207 WP_058706175.1 hypothetical protein -
FOB88_RS03780 190317..191849 - 1533 WP_176017549.1 phage N-6-adenine-methyltransferase -
FOB88_RS03785 192324..192605 - 282 WP_176017550.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 184282..231765 47483


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(6-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(56-99)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14985.23 Da        Isoelectric Point: 10.1741

>T160597 WP_176017547.1 NZ_CP054912:187535-187927 [Pantoea ananatis]
MGFTLYVHKRFDRVFKKTRLTDSVLCYAAGDVFTGVFEADLGGGVIKKRLALHQGKRGGVRTVIFFRQGTNLVYYDGWVK
NLSRKYAREIDEDQLDTYRDVARMFFRANSEVTSLLVRSGMVREVKCNEN

Download         Length: 393 bp

>T160597 NZ_CP070586:c2703837-2702515 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCTGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACACTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCGGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCGCCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGAGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13096.14 Da        Isoelectric Point: 7.2076

>AT160597 WP_014605595.1 NZ_CP054912:187917-188270 [Pantoea ananatis]
MKTEPAELSELLEDAKAFHALGLATDEEVESIAKRAKNRELRARIASVKPMTATEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHQGI

Download         Length: 354 bp

>AT160597 NZ_CP070586:c2704103-2703837 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References