Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 97529..98436 Replicon plasmid unnamed1
Accession NZ_CP054909
Organism Pantoea ananatis strain FDAARGOS_680

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FOB88_RS00455 Protein ID WP_176017156.1
Coordinates 97969..98436 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A8A4JZ23
Locus tag FOB88_RS00450 Protein ID WP_014598335.1
Coordinates 97529..97972 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB88_RS00420 92653..93039 - 387 WP_176017154.1 pyrimidine utilization protein C -
FOB88_RS00425 93065..93817 - 753 WP_014604633.1 pyrimidine utilization protein B -
FOB88_RS00430 93814..94905 - 1092 WP_013027866.1 pyrimidine utilization protein A -
FOB88_RS00435 95304..95993 + 690 WP_014598333.1 HTH-type transcriptional regulator RutR -
FOB88_RS00440 96069..96764 - 696 WP_176017155.1 hypothetical protein -
FOB88_RS00445 96918..97142 - 225 WP_013027863.1 KTSC domain-containing protein -
FOB88_RS00450 97529..97972 + 444 WP_014598335.1 DUF2384 domain-containing protein Antitoxin
FOB88_RS00455 97969..98436 + 468 WP_176017156.1 RES family NAD+ phosphorylase Toxin
FOB88_RS00460 99081..100475 + 1395 WP_014333136.1 flagellar filament capping protein FliD -
FOB88_RS00465 101160..102095 + 936 WP_013027859.1 hypothetical protein -
FOB88_RS00470 102157..102729 - 573 WP_176017240.1 NAD(P)H-dependent oxidoreductase -
FOB88_RS00475 102817..103050 + 234 WP_176017157.1 DUF333 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fliC 1..283516 283516


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-145)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(31-89)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17235.75 Da        Isoelectric Point: 5.1570

>T160591 WP_176017156.1 NZ_CP054909:97969-98436 [Pantoea ananatis]
MKLYRMTKTRYLGSAWSGFGAREGGGRWNSVGVSMVYASETASLTMLETLIHLQSASVLDFFTLMSIDVPDRLIEWIDIK
QLPDDWAAPEAPAALRLFGDAWIQSGGSVALRVPSVLSPVESNYLLNPEHPEFSAIVRQAVNIPFLFDARFSRQV

Download         Length: 468 bp

>T160591 NZ_CP070586:239357-239842 [Klebsiella pneumoniae]
GTGGGACGTATAACCGCGCCCGAGCCGTTATCCAGCGCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGAAGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGCAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCGCGGAAAAGGGCTTGGCGCTGATTT
ACTTCATGATGCAGTACTTCGTTGCTATCGGGTTGCCGAGAATATAGGTGTACGTGCAATCATGGTTCATGCGCTCACAG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAACCATCACAAACTCAGCCGCGGACACTGTTCCTCAGACTCCCT
CAGTAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16375.69 Da        Isoelectric Point: 7.0208

>AT160591 WP_014598335.1 NZ_CP054909:97529-97972 [Pantoea ananatis]
MKQFTLPVSAAEPDRLWQFAGLSSADGVMLMDQIDDGLDGTVASRIVTWAQISQAELRRMTGIAGSTFTRGVKSRFTAEQ
SERLVRFIRVMDRAVELFEGDKEKARQWLNEPARALGNKKPADLVASETGAYEVLKLITRLEHGVYS

Download         Length: 444 bp

>AT160591 NZ_CP070586:239103-239369 [Klebsiella pneumoniae]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCCGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References