Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE(toxin) |
Location | 4709838..4710303 | Replicon | chromosome |
Accession | NZ_CP054880 | ||
Organism | Pseudomonas sp. 43A |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A7H8GNS0 |
Locus tag | HUW52_RS20595 | Protein ID | WP_016983362.1 |
Coordinates | 4710019..4710303 (+) | Length | 95 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A7H8GW22 |
Locus tag | HUW52_RS20590 | Protein ID | WP_026000469.1 |
Coordinates | 4709838..4710029 (+) | Length | 64 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HUW52_RS20575 | 4705261..4707495 | + | 2235 | WP_175554743.1 | cadherin-like domain-containing protein | - |
HUW52_RS20580 | 4707568..4708032 | + | 465 | WP_175554744.1 | curlin | - |
HUW52_RS20585 | 4708060..4709511 | + | 1452 | WP_175554745.1 | curlin | - |
HUW52_RS20590 | 4709838..4710029 | + | 192 | WP_026000469.1 | hypothetical protein | Antitoxin |
HUW52_RS20595 | 4710019..4710303 | + | 285 | WP_016983362.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HUW52_RS20600 | 4711133..4711606 | - | 474 | WP_175554746.1 | hypothetical protein | - |
HUW52_RS20605 | 4712458..4713318 | - | 861 | WP_026000822.1 | curli production assembly/transporter CsgG | - |
HUW52_RS20610 | 4713348..4713779 | - | 432 | WP_016987875.1 | curli production assembly protein CsgF | - |
HUW52_RS20615 | 4713776..4714168 | - | 393 | WP_175554747.1 | curli production assembly/transport protein CsgE | - |
HUW52_RS20620 | 4714165..4714704 | - | 540 | WP_175554748.1 | type II secretion system protein | - |
HUW52_RS20625 | 4714679..4715053 | - | 375 | WP_007919395.1 | type II secretion system GspH family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 95 a.a. Molecular weight: 10866.69 Da Isoelectric Point: 10.6629
>T160587 WP_016983362.1 NZ_CP054880:4710019-4710303 [Pseudomonas sp. 43A]
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALCWHPHLYRKGRSPGTREIVVSPNYLVVYQVADQIEIVS
ILHARQEYPRRDPG
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALCWHPHLYRKGRSPGTREIVVSPNYLVVYQVADQIEIVS
ILHARQEYPRRDPG
Download Length: 285 bp
>T160587 NZ_CP070579:c4957260-4956892 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA
Antitoxin
Download Length: 64 a.a. Molecular weight: 7146.94 Da Isoelectric Point: 3.8576
>AT160587 WP_026000469.1 NZ_CP054880:4709838-4710029 [Pseudomonas sp. 43A]
MIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMEEINALMESMRKSADAD
MIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMEEINALMESMRKSADAD
Download Length: 192 bp
>AT160587 NZ_CP070579:c4957478-4957257 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7H8GNS0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7H8GW22 |