Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4709838..4710303 Replicon chromosome
Accession NZ_CP054880
Organism Pseudomonas sp. 43A

Toxin (Protein)


Gene name relE Uniprot ID A0A7H8GNS0
Locus tag HUW52_RS20595 Protein ID WP_016983362.1
Coordinates 4710019..4710303 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7H8GW22
Locus tag HUW52_RS20590 Protein ID WP_026000469.1
Coordinates 4709838..4710029 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUW52_RS20575 4705261..4707495 + 2235 WP_175554743.1 cadherin-like domain-containing protein -
HUW52_RS20580 4707568..4708032 + 465 WP_175554744.1 curlin -
HUW52_RS20585 4708060..4709511 + 1452 WP_175554745.1 curlin -
HUW52_RS20590 4709838..4710029 + 192 WP_026000469.1 hypothetical protein Antitoxin
HUW52_RS20595 4710019..4710303 + 285 WP_016983362.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HUW52_RS20600 4711133..4711606 - 474 WP_175554746.1 hypothetical protein -
HUW52_RS20605 4712458..4713318 - 861 WP_026000822.1 curli production assembly/transporter CsgG -
HUW52_RS20610 4713348..4713779 - 432 WP_016987875.1 curli production assembly protein CsgF -
HUW52_RS20615 4713776..4714168 - 393 WP_175554747.1 curli production assembly/transport protein CsgE -
HUW52_RS20620 4714165..4714704 - 540 WP_175554748.1 type II secretion system protein -
HUW52_RS20625 4714679..4715053 - 375 WP_007919395.1 type II secretion system GspH family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10866.69 Da        Isoelectric Point: 10.6629

>T160587 WP_016983362.1 NZ_CP054880:4710019-4710303 [Pseudomonas sp. 43A]
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALCWHPHLYRKGRSPGTREIVVSPNYLVVYQVADQIEIVS
ILHARQEYPRRDPG

Download         Length: 285 bp

>T160587 NZ_CP070579:c4957260-4956892 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7146.94 Da        Isoelectric Point: 3.8576

>AT160587 WP_026000469.1 NZ_CP054880:4709838-4710029 [Pseudomonas sp. 43A]
MIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMEEINALMESMRKSADAD

Download         Length: 192 bp

>AT160587 NZ_CP070579:c4957478-4957257 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7H8GNS0

Antitoxin

Source ID Structure
AlphaFold DB A0A7H8GW22

References