Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 4430100..4430653 Replicon chromosome
Accession NZ_CP054871
Organism Pseudomonas protegens strain PPRAR07

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HUT23_RS19985 Protein ID WP_243433848.1
Coordinates 4430100..4430354 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HUT23_RS19990 Protein ID WP_102864761.1
Coordinates 4430381..4430653 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUT23_RS19965 (HUT23_19965) 4425740..4426708 - 969 WP_210458397.1 hypothetical protein -
HUT23_RS19970 (HUT23_19970) 4427057..4427440 + 384 WP_210458396.1 nucleotide pyrophosphohydrolase -
HUT23_RS19975 (HUT23_19975) 4427465..4429339 + 1875 WP_210458395.1 DUF2075 domain-containing protein -
HUT23_RS19980 (HUT23_19980) 4429630..4430022 + 393 WP_210483643.1 DUF3077 domain-containing protein -
HUT23_RS19985 (HUT23_19985) 4430100..4430354 - 255 WP_243433848.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HUT23_RS19990 (HUT23_19990) 4430381..4430653 - 273 WP_102864761.1 CopG family ribbon-helix-helix protein Antitoxin
HUT23_RS19995 (HUT23_19995) 4431014..4433047 - 2034 WP_210483641.1 LTA synthase family protein -
HUT23_RS20000 (HUT23_20000) 4433097..4433708 - 612 WP_210483637.1 hypothetical protein -
HUT23_RS20005 (HUT23_20005) 4433708..4435003 - 1296 WP_210483634.1 sialidase family protein -
HUT23_RS20010 (HUT23_20010) 4435049..4435594 - 546 WP_210483631.1 cytochrome b/b6 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9828.21 Da        Isoelectric Point: 4.9002

>T160556 WP_243433848.1 NZ_CP054871:c4430354-4430100 [Pseudomonas protegens]
MERCRQFLVEKGPLIAQRAAQVIERQIARLEEDPEIGRPFPELPELRELIIEFGDSGYVALYRHERADDAVYLLAFRHQK
EAGY

Download         Length: 255 bp

>T160556 NZ_CP070569:c1682424-1682239 [Proteus mirabilis]
TTGAAAAGTTCGGAACTGATTAAGTTGTTAGAAAAAAACGGATGGATACTTGATAGAATAAAAGGAAGTCATCATCAATT
TACTCACCCTGATTTTTCTTTTGTTGTAACAGTACCGCATCCAAGAAAAGATTTAAAAAAAGGAACATTAAATCAAATTA
TTAAAAGTGCCAAACTGAAAAATTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10466.69 Da        Isoelectric Point: 6.0866

>AT160556 WP_102864761.1 NZ_CP054871:c4430653-4430381 [Pseudomonas protegens]
MATSIKIDDELKKRIQHLAGLRQRSSHWIMREAIAQYVEREEAREGFKQEALASWAAYQETGRHLTGEETRAWLNTWGTE
AEAELPKCHD

Download         Length: 273 bp

>AT160556 NZ_CP070569:c1682192-1681779 [Proteus mirabilis]
ATGTTATATCCAGCCTTTATTGAAATTGATGAAGATGGTAGCGCAAGTGGCTGGTTCCCTGATATTGATGGTTGCATCTT
TGCGGGGGACAGTATTGAAGAAGCTCACGCAGATGCGAGGAGCGCTATTGATGCCCATTTTGAATTGTTAAGCGAGAAGG
GTTTAGATATCCCCTCTCCAAAATCTCAACAAGAGCATTTAATTAATTCTAGTGGTGATTACAATAATGGAATATGGCTT
TTAGTTGATGTTGATATGGATAAATACGACGGACGAGCAGAGCGTATTAATATCACATTGCCACATCGATTATTGAGTCG
CATCGATACTATCGTAAAAACAAATCCTGAATATGGGAGTCGTAGCGGATTTATTGCCACAGCAACCCGTAAAGAACTCC
AAAAGAATATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References