Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/couple_hipB(antitoxin)
Location 3900466..3901068 Replicon chromosome
Accession NZ_CP054861
Organism Martelella sp. NC20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HQ843_RS18705 Protein ID WP_180901741.1
Coordinates 3900466..3900711 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HQ843_RS18710 Protein ID WP_180901740.1
Coordinates 3900718..3901068 (+) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ843_RS18675 3895470..3896210 - 741 WP_180901747.1 hypothetical protein -
HQ843_RS18680 3896384..3897607 + 1224 WP_180901746.1 HPP family protein -
HQ843_RS18685 3897760..3898395 - 636 WP_180901745.1 antitermination protein NusG -
HQ843_RS18690 3898392..3899123 - 732 WP_180901744.1 hypothetical protein -
HQ843_RS18695 3899116..3899517 - 402 WP_180901743.1 hypothetical protein -
HQ843_RS18700 3899546..3900376 - 831 WP_180901742.1 DUF1376 domain-containing protein -
HQ843_RS18705 3900466..3900711 + 246 WP_180901741.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
HQ843_RS18710 3900718..3901068 + 351 WP_180901740.1 helix-turn-helix transcriptional regulator Antitoxin
HQ843_RS18715 3901101..3901841 - 741 WP_180902130.1 hypothetical protein -
HQ843_RS18720 3902116..3902694 - 579 WP_180901739.1 hypothetical protein -
HQ843_RS18725 3902696..3903175 - 480 WP_180901738.1 hypothetical protein -
HQ843_RS18730 3903348..3903563 - 216 WP_180902129.1 helix-turn-helix domain-containing protein -
HQ843_RS18735 3903649..3904437 + 789 WP_180901737.1 XRE family transcriptional regulator -
HQ843_RS18740 3904727..3905272 + 546 WP_180901736.1 hypothetical protein -
HQ843_RS18745 3905275..3905517 + 243 WP_180901735.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3855893..3906568 50675


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(62-115)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9152.84 Da        Isoelectric Point: 10.8582

>T160531 WP_180901741.1 NZ_CP054861:3900466-3900711 [Martelella sp. NC20]
MKTIRYTKVAMKSIQRMQPKRRNAIIAKIEAFASGETVDLKKLQGSPYFRIRVGSDRIILDDQGLVVMIIDAGPRGGIYK
E

Download         Length: 246 bp

>T160531 NZ_CP070564:211534-212451 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12695.34 Da        Isoelectric Point: 4.3047

>AT160531 WP_180901740.1 NZ_CP054861:3900718-3901068 [Martelella sp. NC20]
MGEVQKITIEGNNYVLLREADYDDMLDSLHARAVMAGVDAGEETYPHELIVALSDETQSRLRVWRKYRGLTMKALAEKAG
ISQPYLSDIENGKADGSISAIKALAAALDVDIDDLV

Download         Length: 351 bp

>AT160531 NZ_CP070564:210770-211528 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGTCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References