Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 181186..181871 Replicon plasmid unnamed2
Accession NZ_CP054860
Organism Martelella sp. NC18

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HQ775_RS28865 Protein ID WP_180902599.1
Coordinates 181186..181608 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HQ775_RS28870 Protein ID WP_180902600.1
Coordinates 181605..181871 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ775_RS28850 177031..178035 + 1005 WP_180902596.1 plasmid partitioning protein RepB -
HQ775_RS28855 178241..179557 + 1317 WP_180902597.1 replication initiation protein RepC -
HQ775_RS28860 179758..180852 - 1095 WP_180902598.1 Fic family protein -
HQ775_RS28865 181186..181608 - 423 WP_180902599.1 type II toxin-antitoxin system VapC family toxin Toxin
HQ775_RS28870 181605..181871 - 267 WP_180902600.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HQ775_RS28875 182016..183095 - 1080 WP_180902601.1 tyrosine-type recombinase/integrase -
HQ775_RS28880 183242..184194 + 953 Protein_180 DUF1403 family protein -
HQ775_RS28885 184197..184883 + 687 WP_180902602.1 SMC-Scp complex subunit ScpB -
HQ775_RS28890 185071..185820 + 750 WP_180902603.1 DUF1275 domain-containing protein -
HQ775_RS28895 185932..186762 - 831 WP_180902604.1 DUF3883 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..259503 259503


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-72)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15670.00 Da        Isoelectric Point: 4.6869

>T160528 WP_180902599.1 NZ_CP054860:c181608-181186 [Martelella sp. NC18]
VNLLLDTNVLSEVTKPRPEGRVLLWLDGLDEDRCFISVVSLAEIRRGVALMDDGRKRDALAEWLAHDLPQRFEHRVFAVD
ERVALAWGDLMGEAKRRGRGMSSMDGLIAATAMAYDLVLATRNVKDFEGFGMDLIDPWAA

Download         Length: 423 bp

>T160528 NZ_CP070553:2738797-2739150 [Morganella morganii]
GTGTGGAAGATAGTCACAACAGATAATTTTACAGCGTGGTTTGCTGAGCAGGATGACGGAGATCGCGCAGCAATACTGGC
AGCGATGCTGGTATTGGAGAAGCGGGGACCCGGCTTACCAAGGCCGTATGCGGATACTGTAAAAGGTTCCCGGTATACGA
ATATGAAAGAGCTTCGTATACAGAGCAGGGGACAACCGATACGGGCATTTTTTGCATTCGACCCTGAGAGAAGAGGCGTC
TTGCTGTGTGCGGGGTATAAAACCGGCAAAGAAAAACGTTTTTATATGCAGATGATCCCGCAGGCTGACCGTGAGTATAC
AGAATGGCTGAACAGGCCGGAAAACAGGAGTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9837.15 Da        Isoelectric Point: 8.7353

>AT160528 WP_180902600.1 NZ_CP054860:c181871-181605 [Martelella sp. NC18]
MQPVSHDEKNWTVAKAKAKLSEVIERAQSTPQTITRNGKPSVVVVSAEEWQRKVARKGTLAEFLLASPLRGAELDLNRQD
DEPRDLSL

Download         Length: 267 bp

>AT160528 NZ_CP070553:2739153-2739455 [Morganella morganii]
ATGGGAAAGTCACTCAGACAACTGCTGGCTGAGGAAAAGCCGGAAGTCGCGGCTGCTGCACGGGTTCAGGCGGATGAGAT
CCTGCTGAATATCCATCTGGCGGAGCTGCGGGAGAAAGTGAAGAAAACACAGGTGGAAATGGCGCAGGCACTGGGAATAA
AACAGCCGACAGTCGCAGGGATGGAAAAACCGGGGCGTGATGTCAAATTATCCACGCTGAGACGCTATGTGGATGCCATC
GGCGGAAAACTGAATATTGATGTTGAACTGCCGGACGGCACGCATTATATGTTCCGGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References