Detailed information of TA system TA160101

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prpT-prpA/ParE-CC2985
• Location: 101939..102488
• Replicon: plasmid unnamed1
• Accession: NZ_CP054717
• Organism: Salmonella enterica strain 85-0120

Toxin (Protein)

• Gene name: PrpT
• Uniprot ID: -
• Locus tag: HPG84_RS23815
• Protein ID: WP_171774032.1
• Coordinates: 101939..102235 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: PrpA
• Uniprot ID: -
• Locus tag: HPG84_RS23820
• Protein ID: WP_171774031.1
• Coordinates: 102222..102488 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HPG84_RS23800	99334..99951	+	618	WP_174896731.1	recombinase family protein	-
HPG84_RS23805	100058..100918	+	861	WP_174896803.1	alpha/beta hydrolase	-
HPG84_RS23810	100972..101640	-	669	Protein_116	site-specific integrase	-
HPG84_RS23815	101939..102235	-	297	WP_171774032.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HPG84_RS23820	102222..102488	-	267	WP_171774031.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
HPG84_RS23825	102945..103238	-	294	WP_174896804.1	hypothetical protein	-
HPG84_RS23830	103235..103687	-	453	WP_171774006.1	phage holin family protein	-
HPG84_RS23835	103793..104146	-	354	WP_171774005.1	hypothetical protein	-
HPG84_RS23840	104199..104447	-	249	WP_174896805.1	DUF883 family protein	-
HPG84_RS23845	105312..105677	+	366	WP_171774003.1	hypothetical protein	-
HPG84_RS23850	105717..106844	+	1128	WP_171774002.1	acyl-protein synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..162029	162029

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 14588.50 Da
• Isoelectric Point: 5.5500

>T160101 WP_171774032.1 NZ_CP054717:c102235-101939 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 297 bp

>T160101 NZ_CP070292:4080892-4081233 [Escherichia albertii]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGCCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGCGATAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCCCCCGCCGCCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAAGCAGGTGCAGGAATTTATTGGGGTGATTGC
CGGTAAACAGAAAGTCGCCTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 13116.73 Da
• Isoelectric Point: 5.5500

>AT160101 WP_171774031.1 NZ_CP054717:c102488-102222 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFF

Nucleotide

• Length: 267 bp

>AT160101 NZ_CP070292:c4080897-4080821 [Escherichia albertii]
AGTCATGATTACTATTCTCCATAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT