Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 93342..93870 Replicon plasmid unnamed2
Accession NZ_CP054703
Organism Vibrio alginolyticus strain GS_MYPK1

Toxin (Protein)


Gene name relE Uniprot ID A0A1W6UUU0
Locus tag HUO05_RS24440 Protein ID WP_025767362.1
Coordinates 93586..93870 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7H8DZ36
Locus tag HUO05_RS24435 Protein ID WP_025767361.1
Coordinates 93342..93596 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUO05_RS24395 88675..89049 - 375 WP_025767354.1 hypothetical protein -
HUO05_RS24400 89230..90060 - 831 WP_025767355.1 hypothetical protein -
HUO05_RS24405 90207..90383 - 177 WP_158501046.1 hypothetical protein -
HUO05_RS24410 90394..90987 - 594 WP_025767356.1 hypothetical protein -
HUO05_RS24415 91198..91536 + 339 WP_025767357.1 hypothetical protein -
HUO05_RS24420 91585..91818 - 234 WP_025767358.1 hypothetical protein -
HUO05_RS24425 91837..92271 - 435 WP_025767359.1 hypothetical protein -
HUO05_RS24430 92337..93089 - 753 WP_025767360.1 hypothetical protein -
HUO05_RS24435 93342..93596 + 255 WP_025767361.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HUO05_RS24440 93586..93870 + 285 WP_025767362.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HUO05_RS24445 94107..94295 + 189 WP_025767364.1 hypothetical protein -
HUO05_RS24450 94308..94571 + 264 WP_025767365.1 hypothetical protein -
HUO05_RS24455 94806..95126 - 321 WP_025767366.1 hypothetical protein -
HUO05_RS24460 95377..96123 + 747 WP_025767367.1 hypothetical protein -
HUO05_RS24465 97362..97670 + 309 WP_025767368.1 hypothetical protein -
HUO05_RS24470 97970..98290 + 321 WP_025767369.1 hypothetical protein -
HUO05_RS24475 98300..98503 + 204 WP_025767370.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..266388 266388


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11103.10 Da        Isoelectric Point: 10.6691

>T160092 WP_025767362.1 NZ_CP054703:93586-93870 [Vibrio alginolyticus]
MTYKLVFKTEAEKEWRKLDSTIKSQFKKKLIERLENPHVPTAKLSSMENCYKIKLRSAGYRLVYQVRDQEVIISVVAVGK
RERNQVYKIAAKRV

Download         Length: 285 bp

>T160092 NZ_CP070292:1156485-1156637 [Escherichia albertii]
ATGCTGACAAAATATGCCCTTGTGGCAATCATAGTGCTGTGTTGTACAGTGCTGGGATTCACGCTGATGGTAGGCGACTC
GTTGTGTGAGTTGAGTATCAGAGAACGTGGTATGGAGTTTAAGGCAGTTCTCGCTTACGAATCGAAGAAGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9460.78 Da        Isoelectric Point: 3.9953

>AT160092 WP_025767361.1 NZ_CP054703:93342-93596 [Vibrio alginolyticus]
MPTIRPILADNSTSISELKKNPMAVIEQADGFPVAVLNRNQPAFYCVPADAYEMLMDKLEDIELAQIVKEREHSEEVEIS
IDDL

Download         Length: 255 bp

>AT160092 NZ_CP070292:c1156443-1156391 [Escherichia albertii]
TTAGGTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1W6UUU0

Antitoxin

Source ID Structure
AlphaFold DB A0A7H8DZ36

References