Detailed information of TA system TA160079

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 4270258..4270867
• Replicon: chromosome
• Accession: NZ_CP054698
• Organism: Nostoc edaphicum CCNP1411

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HUN01_RS20445
• Protein ID: WP_181927732.1
• Coordinates: 4270258..4270620 (-)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HUN01_RS20450
• Protein ID: WP_181927733.1
• Coordinates: 4270610..4270867 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HUN01_RS20435	4266403..4269195	-	2793	WP_181927730.1	preprotein translocase subunit SecA	-
HUN01_RS20440	4269490..4270083	-	594	WP_181927731.1	cytochrome C	-
HUN01_RS20445	4270258..4270620	-	363	WP_181927732.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HUN01_RS20450	4270610..4270867	-	258	WP_181927733.1	hypothetical protein	Antitoxin
HUN01_RS20455	4271140..4272048	-	909	WP_181927734.1	MoxR family ATPase	-
HUN01_RS20460	4272191..4273255	-	1065	WP_181927735.1	bifunctional riboflavin kinase/FAD synthetase	-
HUN01_RS20465	4273659..4274555	-	897	WP_181927736.1	MBL fold metallo-hydrolase	-
HUN01_RS20470	4274842..4275639	-	798	WP_181927737.1	5'/3'-nucleotidase SurE	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (3-131)

Antitoxin

• Flavinator of succinate dehydrogenase (7-79)

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 14027.80 Da
• Isoelectric Point: 5.2358

>T160079 WP_181927732.1 NZ_CP054698:c4270620-4270258 [Nostoc edaphicum CCNP1411]
MQSDNTVLIRFSDEFEQELYRLSKRFRNIRSDVQPIIEQLQQGSFVGAHIAGIGEEYIVYKVRVRNSNIQKGKSAGYRLI
YQVESPTSILLLTIYSKSDREDINVNEIRDIMADFYSRED

Nucleotide

• Length: 363 bp

>T160079 NZ_CP070290:884609-885013 [Escherichia albertii]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCGCAGTGGCTCTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGCTATTTTACTCATGCCCTGGCCGCTAAGTTATACCCCGTTATGGATGGTGTTGCTTTCGCTGGTGGTGTTTGATTGCG
TCCGCAGTCAGCGGCGCATTAATGCTCGTCAGGGGGAGATTCGCCTGTTGATGGATGGGCGTTTACGCTGGCAGGGGCAG
GAGTGGAGCATCGTCAGAGCGCCGTGGATGATTAAAACTGGCATGATGTTGCGTTTACTCTCTGATAGTGGCAAACGTCA
GCACCTGTGGCTGGCAGCCGACAGTATGGATGAAGCTGAATGGCGGGATTTGCGGCGAATTTTGTTACAACAAGAGATAC
AGTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9488.61 Da
• Isoelectric Point: 4.1957

>AT160079 WP_181927733.1 NZ_CP054698:c4270867-4270610 [Nostoc edaphicum CCNP1411]
MKAIEVTGRIDSQGNLVLDEPIQGNTYPHQVRVIVLVPEQAEAEEVDPDDTPVEEIKASLRRALQQAKAGQTRPISELWD
RIDAE

Nucleotide

• Length: 258 bp

>AT160079 NZ_CP070290:884362-884628 [Escherichia albertii]
ATGGACATTAACAATAAAGCCCGCATTCACTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGATAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGACTGCTGGAATGTGACGATCCCGATT
TATTCAACTGGTTGATGAATCACGGTAAACCGGCCGACGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA