Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2289798..2290032 Replicon chromosome
Accession NZ_CP054662
Organism Escherichia coli strain IGC_RcoliRes_1.1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2289928..2290031 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2289798..2290032 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUR93_RS11190 2286353..2287015 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUR93_RS11195 2287039..2287695 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
HUR93_RS11200 2287797..2288027 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUR93_RS11205 2288166..2288540 + 375 WP_000204699.1 CopC domain-containing protein YobA -
HUR93_RS11210 2288544..2289416 + 873 WP_061892384.1 copper homeostasis membrane protein CopD -
HUR93_RS11215 2289429..2289770 + 342 WP_000976492.1 YebY family protein -
- 2289798..2290032 - 235 - - Antitoxin
- 2289928..2290031 + 104 - - Toxin
HUR93_RS11220 2290163..2291239 - 1077 WP_001189085.1 phage integrase Arm DNA-binding domain-containing protein -
HUR93_RS11225 2291205..2291486 - 282 WP_001311878.1 excisionase -
HUR93_RS11230 2291593..2291781 - 189 WP_024165285.1 DUF1187 family protein -
- 2291597..2291775 + 179 NuclAT_1 - -
- 2291597..2291775 + 179 NuclAT_1 - -
- 2291597..2291775 + 179 NuclAT_1 - -
- 2291597..2291775 + 179 NuclAT_1 - -
HUR93_RS11235 2291774..2291968 - 195 WP_001307771.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
HUR93_RS11240 2292001..2292681 - 681 WP_000186708.1 YqaJ viral recombinase family protein -
HUR93_RS11245 2292678..2293463 - 786 WP_001484907.1 phage recombination protein Bet -
HUR93_RS11250 2293469..2293765 - 297 WP_001484906.1 host-nuclease inhibitor Gam family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2282388..2338189 55801


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T160005 NZ_CP054662:2289928-2290031 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 235 bp

>AT160005 NZ_CP054662:c2290032-2289798 [Escherichia coli]
TAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References