Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PrlF(antitoxin)
Location 1734072..1734636 Replicon chromosome
Accession NZ_CP054619
Organism Azospirillum oryzae strain KACC 14407

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag HUE56_RS17265 Protein ID WP_149197000.1
Coordinates 1734072..1734434 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag HUE56_RS17270 Protein ID WP_149197001.1
Coordinates 1734421..1734636 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUE56_RS17240 1729183..1730037 - 855 WP_149196997.1 squalene/phytoene synthase family protein -
HUE56_RS17245 1730161..1731033 + 873 WP_149196998.1 squalene/phytoene synthase family protein -
HUE56_RS17250 1731095..1732033 + 939 WP_149197648.1 presqualene diphosphate synthase HpnD -
HUE56_RS17255 1732033..1733409 + 1377 WP_149196999.1 hydroxysqualene dehydroxylase HpnE -
HUE56_RS17260 1733415..1734008 + 594 WP_109075681.1 superoxide dismutase -
HUE56_RS17265 1734072..1734434 - 363 WP_149197000.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
HUE56_RS17270 1734421..1734636 - 216 WP_149197001.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
HUE56_RS17275 1734699..1735076 - 378 WP_149197002.1 Mth938-like domain-containing protein -
HUE56_RS17280 1735107..1736063 - 957 WP_149197003.1 protein translocase subunit SecF -
HUE56_RS17285 1736075..1737673 - 1599 WP_149197004.1 protein translocase subunit SecD -
HUE56_RS17290 1737799..1738224 - 426 WP_149197005.1 preprotein translocase subunit YajC -
HUE56_RS17295 1738477..1739343 + 867 WP_149197006.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-106)

Antitoxin

PrlF antitoxin

(4-52)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 12800.67 Da        Isoelectric Point: 6.7262

>T159982 WP_149197000.1 NZ_CP054619:c1734434-1734072 [Azospirillum oryzae]
MPTFEIWNIVKVPFPYADRPARQRRPALVVAAEDLEASHSLLWVLMITSAENRGWPSDVPVGDLETAGLPAPSVVRTAKV
AVIDARDAEPLGSLAAGDRGAVSRQVGHHLAGMLKAGRDA

Download         Length: 363 bp

>T159982 NZ_CP070229:c3360023-3359538 [Escherichia coli]
ATGGGAATAACGGCTCCTACTCCCCTAACGTCTGAACATAATCTGGCTGACTTTTGCTGTTCCGATCACGGGATGAATGA
ATGGCTAAAAAAGAAAGCGTTAAAAAATCACAGCTCCAGTCTGTCTCGTGTTTACGTTATCTGTATTGCCAATACCCGCC
AGGTAATCGGCTATTACTGCCTTTCTACAGGCAGTATTCAACGTAATTTGGCCCCTGGAGCCATGCGACGTAATGCTCCC
GAATCGTTGCCTGTTGTCGTATTAGGCAGACTGGCAATTGATCAAGCCTGGGCAGGTAAAGGGCTGGGCGTCGCATTGTT
GAAAGATGCAGTCTATCGCACAATGTCCATAGCTCAACAGGTAGGGGTTCGGGCGCTCATTGTTCATGCCTTAGACGATT
CAGTACGCAATTTCTATCTGAAGTATGCCTTTGTACCTTCACCATTCCAGTCACTTACCTTACTGTATCCCATTACTCTG
GAGTAA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 7849.79 Da        Isoelectric Point: 4.5026

>AT159982 WP_149197001.1 NZ_CP054619:c1734636-1734421 [Azospirillum oryzae]
MITSKLTSKAQTTIPQPVRAALGLHEGDEIAYRIEDGRVILTRAAPAAAEDPFRCFTEWDSEADRQAYADL

Download         Length: 216 bp

>AT159982 NZ_CP070229:c3360292-3360014 [Escherichia coli]
ATGAAACCGGAAAGCAAAGAAACACCAATCAATATCAGGGCGAAAGCCTCACAGCGTGACCTGATTGATATGGCAGCGAA
TCTGGTCGCAAAATCGCGCACTGATTTTATGCTGGATGCCGCATGCCGTGAAGCGCAAGACATCTTATTAGATCAACGAC
TATTCATCCTTGATGACGAGCAATACGATGCGTTTCTGGCTGCCCTGGACGCCCCCATCACTGCTGAGCGTCAGGCCAAA
ATTAACGCGTTGATGAATCGTAAATCGCCATGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References