Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 679439..680028 Replicon chromosome
Accession NZ_CP054619
Organism Azospirillum oryzae strain KACC 14407

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag HUE56_RS12245 Protein ID WP_149197917.1
Coordinates 679439..679786 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag HUE56_RS12250 Protein ID WP_174757220.1
Coordinates 679783..680028 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUE56_RS12220 675634..675954 + 321 WP_109075942.1 hypothetical protein -
HUE56_RS12225 676011..676229 - 219 WP_149197914.1 hypothetical protein -
HUE56_RS12230 676562..676936 + 375 WP_085090219.1 DUF952 domain-containing protein -
HUE56_RS12235 676933..678006 + 1074 WP_149197915.1 quinone-dependent dihydroorotate dehydrogenase -
HUE56_RS12240 678055..679428 + 1374 WP_149197916.1 EAL domain-containing protein -
HUE56_RS12245 679439..679786 - 348 WP_149197917.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
HUE56_RS12250 679783..680028 - 246 WP_174757220.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
HUE56_RS12255 680231..682195 + 1965 WP_136704571.1 threonine--tRNA ligase -
HUE56_RS12260 682280..682807 + 528 WP_042696225.1 translation initiation factor IF-3 -
HUE56_RS12265 682880..684256 - 1377 WP_149197919.1 alpha/beta hydrolase -
HUE56_RS12270 684360..684557 - 198 WP_149197920.1 DUF2783 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-115)

Antitoxin

SpoVT-AbrB domain

(7-47)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12469.42 Da        Isoelectric Point: 9.4920

>T159980 WP_149197917.1 NZ_CP054619:c679786-679439 [Azospirillum oryzae]
MTDDKWEPEAGDLIWTDFDPRTGREQGGRRPALIVSPHAFWQATRFAIVCPITTRVRPFPSSAVLPPGPPISGEILTSHV
RSIDTMARPLLFSGARAPSAILAEVRGKLAALIGL

Download         Length: 348 bp

>T159980 NZ_CP054619:c679786-679439 [Azospirillum oryzae]
ATGACCGACGATAAATGGGAACCGGAAGCCGGCGATCTCATCTGGACTGACTTCGATCCACGGACGGGGCGTGAGCAGGG
CGGGCGCAGACCAGCACTGATCGTGTCACCCCATGCTTTTTGGCAGGCGACACGCTTTGCAATCGTATGCCCGATCACCA
CGCGCGTTCGCCCGTTTCCCAGCAGTGCCGTATTGCCGCCGGGTCCGCCGATTTCCGGCGAAATCCTGACCAGCCATGTT
CGCAGCATCGACACCATGGCCCGGCCGCTGCTGTTTTCCGGCGCACGCGCTCCATCGGCAATCCTGGCCGAAGTCCGCGG
AAAGCTCGCCGCGCTGATTGGACTTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9090.28 Da        Isoelectric Point: 4.6158

>AT159980 WP_174757220.1 NZ_CP054619:c680028-679783 [Azospirillum oryzae]
MQVQLARWGNSLGIRIPKDIASQVGLRDGTRVDIHAEGDRIVITADRPRYSLDELMKGVTPEAMREAFDWGPDVGREVVE
E

Download         Length: 246 bp

>AT159980 NZ_CP054619:c680028-679783 [Azospirillum oryzae]
ATGCAGGTCCAACTCGCACGATGGGGCAACAGCCTGGGCATCCGCATTCCCAAGGACATCGCCAGTCAGGTGGGGCTGCG
CGACGGCACAAGGGTGGACATTCACGCCGAAGGCGATCGGATCGTCATCACCGCAGATCGCCCCCGCTACAGCCTCGATG
AACTCATGAAAGGCGTCACGCCGGAGGCGATGCGGGAGGCGTTCGACTGGGGTCCCGATGTTGGCCGTGAGGTCGTTGAG
GAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References