Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1613279..1613820 Replicon chromosome
Accession NZ_CP054571
Organism Achromobacter xylosoxidans strain FDAARGOS_789

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FOC83_RS07465 Protein ID WP_026384571.1
Coordinates 1613279..1613554 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FOC83_RS07470 Protein ID WP_024069590.1
Coordinates 1613554..1613820 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOC83_RS07445 1609231..1610154 + 924 WP_006385014.1 ABC transporter permease -
FOC83_RS07450 1610160..1611026 + 867 WP_024069588.1 ABC transporter permease -
FOC83_RS07455 1611084..1612823 + 1740 WP_024069589.1 hypothetical protein -
FOC83_RS07460 1612836..1613273 + 438 WP_020928528.1 acetyltransferase -
FOC83_RS07465 1613279..1613554 - 276 WP_026384571.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOC83_RS07470 1613554..1613820 - 267 WP_024069590.1 ribbon-helix-helix domain-containing protein Antitoxin
FOC83_RS07475 1614067..1614594 + 528 WP_024069591.1 sigma-70 family RNA polymerase sigma factor -
FOC83_RS07480 1614680..1615636 + 957 WP_054498804.1 FecR domain-containing protein -
FOC83_RS07485 1615896..1618322 + 2427 WP_070543066.1 TonB-dependent receptor -
FOC83_RS07490 1618375..1618581 - 207 WP_006385007.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10710.42 Da        Isoelectric Point: 10.4170

>T159902 WP_026384571.1 NZ_CP054571:c1613554-1613279 [Achromobacter xylosoxidans]
MEMKWTSKALSDLARLHEFLAAVNRPAAVRAVQALVKASSVLPTNSRIGEQLFQFEPREVRRILVGEYEIRYEIRDSIIY
VLRLWHTRENR

Download         Length: 276 bp

>T159902 NZ_CP070170:80082-80189 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGTTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9699.04 Da        Isoelectric Point: 4.5720

>AT159902 WP_024069590.1 NZ_CP054571:c1613820-1613554 [Achromobacter xylosoxidans]
MSPATKVLTAHVPLPLAEKVDQMAVRLDRSRGWIVKQALSAWIAQEEERDKLTEQALADVDAGRIVDDQAVQAWAESLGS
DQPLPLPR

Download         Length: 267 bp

>AT159902 NZ_CP070170:c80034-79968 [Escherichia coli]
GGTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References