Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pemIK/MazF(toxin) |
Location | 2671382..2672024 | Replicon | chromosome |
Accession | NZ_CP054568 | ||
Organism | Bacillus thuringiensis strain FDAARGOS_791 |
Toxin (Protein)
Gene name | pemK | Uniprot ID | J8CWW5 |
Locus tag | FOC85_RS14180 | Protein ID | WP_000635963.1 |
Coordinates | 2671674..2672024 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | pemI | Uniprot ID | R8I8H2 |
Locus tag | FOC85_RS14175 | Protein ID | WP_000004570.1 |
Coordinates | 2671382..2671669 (+) | Length | 96 a.a. |
Genomic Context
Location: 2666698..2667660 (963 bp)
Type: Others
Protein ID: WP_000961158.1
Type: Others
Protein ID: WP_000961158.1
Location: 2668318..2668677 (360 bp)
Type: Others
Protein ID: WP_000635040.1
Type: Others
Protein ID: WP_000635040.1
Location: 2668834..2669784 (951 bp)
Type: Others
Protein ID: WP_025388382.1
Type: Others
Protein ID: WP_025388382.1
Location: 2669903..2671072 (1170 bp)
Type: Others
Protein ID: WP_000390600.1
Type: Others
Protein ID: WP_000390600.1
Location: 2671382..2671669 (288 bp)
Type: Antitoxin
Protein ID: WP_000004570.1
Type: Antitoxin
Protein ID: WP_000004570.1
Location: 2671674..2672024 (351 bp)
Type: Toxin
Protein ID: WP_000635963.1
Type: Toxin
Protein ID: WP_000635963.1
Location: 2672092..2674260 (2169 bp)
Type: Others
Protein ID: WP_000426225.1
Type: Others
Protein ID: WP_000426225.1
Location: 2674630..2675088 (459 bp)
Type: Others
Protein ID: WP_000344244.1
Type: Others
Protein ID: WP_000344244.1
Location: 2667653..2668225 (573 bp)
Type: Others
Protein ID: WP_000906926.1
Type: Others
Protein ID: WP_000906926.1
Location: 2674318..2674434 (117 bp)
Type: Others
Protein ID: WP_001143642.1
Type: Others
Protein ID: WP_001143642.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FOC85_RS14150 | 2666698..2667660 | + | 963 | WP_000961158.1 | UV DNA damage repair endonuclease UvsE | - |
FOC85_RS14155 | 2667653..2668225 | - | 573 | WP_000906926.1 | rhomboid family intramembrane serine protease | - |
FOC85_RS14160 | 2668318..2668677 | + | 360 | WP_000635040.1 | holo-ACP synthase | - |
FOC85_RS14165 | 2668834..2669784 | + | 951 | WP_025388382.1 | outer membrane lipoprotein carrier protein LolA | - |
FOC85_RS14170 | 2669903..2671072 | + | 1170 | WP_000390600.1 | alanine racemase | - |
FOC85_RS14175 | 2671382..2671669 | + | 288 | WP_000004570.1 | antitoxin EndoAI | Antitoxin |
FOC85_RS14180 | 2671674..2672024 | + | 351 | WP_000635963.1 | type II toxin-antitoxin system endoribonuclease NdoA | Toxin |
FOC85_RS14185 | 2672092..2674260 | + | 2169 | WP_000426225.1 | RNA-binding transcriptional accessory protein | - |
FOC85_RS14190 | 2674318..2674434 | - | 117 | WP_001143642.1 | cortex morphogenetic protein CmpA | - |
FOC85_RS14195 | 2674630..2675088 | + | 459 | WP_000344244.1 | SprT family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12974.12 Da Isoelectric Point: 5.7168
>T159897 WP_000635963.1 NZ_CP054568:2671674-2672024 [Bacillus thuringiensis]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEVMMIRVDEALQISLGLIDF
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEVMMIRVDEALQISLGLIDF
Download Length: 351 bp
>T159897 NZ_CP070169:c3446030-3445746 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCTGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCTGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10780.36 Da Isoelectric Point: 8.9605
>AT159897 WP_000004570.1 NZ_CP054568:2671382-2671669 [Bacillus thuringiensis]
VSESSVTTEIVVRLPKQMVTELDGIGKQENKNRHELICQATQLLLRQHKTKKRYQHESMRRGYIEMGKINLGIASEAFLA
EYEAAHTVERLVSGG
VSESSVTTEIVVRLPKQMVTELDGIGKQENKNRHELICQATQLLLRQHKTKKRYQHESMRRGYIEMGKINLGIASEAFLA
EYEAAHTVERLVSGG
Download Length: 288 bp
>AT159897 NZ_CP070169:c3446262-3446020 [Klebsiella pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA