Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 969218..969452 | Replicon | chromosome |
| Accession | NZ_CP054556 | ||
| Organism | Escherichia coli strain LWY24 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 969219..969321 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 969218..969452 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HT750_RS04795 | 966166..967218 | + | 1053 | WP_174617238.1 | recombinase RecT | - |
| HT750_RS04800 | 967282..967476 | + | 195 | WP_010989194.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| HT750_RS04805 | 967469..967657 | + | 189 | WP_024165285.1 | DUF1187 family protein | - |
| - | 967475..967653 | - | 179 | NuclAT_0 | - | - |
| - | 967475..967653 | - | 179 | NuclAT_0 | - | - |
| - | 967475..967653 | - | 179 | NuclAT_0 | - | - |
| - | 967475..967653 | - | 179 | NuclAT_0 | - | - |
| HT750_RS04810 | 967764..968045 | + | 282 | WP_001311878.1 | excisionase | - |
| HT750_RS04815 | 968011..969087 | + | 1077 | WP_001189087.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 969218..969452 | + | 235 | - | - | Antitoxin |
| - | 969219..969321 | - | 103 | - | - | Toxin |
| HT750_RS04820 | 969480..969821 | - | 342 | WP_000976484.1 | YebY family protein | - |
| HT750_RS04825 | 969834..970706 | - | 873 | WP_000879323.1 | copper homeostasis membrane protein CopD | - |
| HT750_RS04830 | 970710..971084 | - | 375 | WP_000168737.1 | CopC domain-containing protein YobA | - |
| HT750_RS04835 | 971223..971453 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HT750_RS04840 | 971555..972211 | + | 657 | WP_000011651.1 | carbon-nitrogen hydrolase family protein | - |
| HT750_RS04845 | 972235..972897 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 920572..976859 | 56287 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T159866 NZ_CP054556:c969321-969219 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT159866 NZ_CP054556:969218-969452 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
