Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/PIN-RelB |
Location | 2130282..2131135 | Replicon | chromosome |
Accession | NZ_CP054525 | ||
Organism | Bifidobacterium longum subsp. infantis strain PI_003 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A7D5BU34 |
Locus tag | HUE62_RS09635 | Protein ID | WP_032745209.1 |
Coordinates | 2130282..2130773 (-) | Length | 164 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q8G4I4 |
Locus tag | HUE62_RS09640 | Protein ID | WP_011068030.1 |
Coordinates | 2130773..2131135 (-) | Length | 121 a.a. |
Genomic Context
Location: 2127206..2127346 (141 bp)
Type: Others
Protein ID: Protein_1870
Type: Others
Protein ID: Protein_1870
Location: 2127387..2128028 (642 bp)
Type: Others
Protein ID: WP_032745208.1
Type: Others
Protein ID: WP_032745208.1
Location: 2128117..2130221 (2105 bp)
Type: Others
Protein ID: Protein_1872
Type: Others
Protein ID: Protein_1872
Location: 2126135..2127037 (903 bp)
Type: Others
Protein ID: WP_032745207.1
Type: Others
Protein ID: WP_032745207.1
Location: 2130282..2130773 (492 bp)
Type: Toxin
Protein ID: WP_032745209.1
Type: Toxin
Protein ID: WP_032745209.1
Location: 2130773..2131135 (363 bp)
Type: Antitoxin
Protein ID: WP_011068030.1
Type: Antitoxin
Protein ID: WP_011068030.1
Location: 2131281..2133980 (2700 bp)
Type: Others
Protein ID: WP_032745210.1
Type: Others
Protein ID: WP_032745210.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HUE62_RS09615 (HUE62_09550) | 2126135..2127037 | - | 903 | WP_032745207.1 | Bax inhibitor-1/YccA family protein | - |
HUE62_RS09620 (HUE62_09555) | 2127206..2127346 | + | 141 | Protein_1870 | LuxR C-terminal-related transcriptional regulator | - |
HUE62_RS09625 (HUE62_09560) | 2127387..2128028 | + | 642 | WP_032745208.1 | GNAT family N-acetyltransferase | - |
HUE62_RS09630 (HUE62_09565) | 2128117..2130221 | + | 2105 | Protein_1872 | DUF262 domain-containing protein | - |
HUE62_RS09635 (HUE62_09570) | 2130282..2130773 | - | 492 | WP_032745209.1 | PIN domain-containing protein | Toxin |
HUE62_RS09640 (HUE62_09575) | 2130773..2131135 | - | 363 | WP_011068030.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
HUE62_RS09645 (HUE62_09580) | 2131281..2133980 | - | 2700 | WP_032745210.1 | aconitate hydratase AcnA | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 18298.86 Da Isoelectric Point: 4.5590
>T159844 WP_032745209.1 NZ_CP054525:c2130773-2130282 [Bifidobacterium longum subsp. infantis]
MTDVSMQRILLDTNVLLDYLLHRDDHAKMAEAVMELGAKNNVTLLCASLSLKDIAYLSSSAIRRECKPNESEVENFTRGF
LSSRVPWRCIEQVKEMCDIVAVDESTCDKAFSLQKRHRDFEDDLIIVAAQQSGANCVVTSDAELISHFPEYCRTPAEIVA
ALE
MTDVSMQRILLDTNVLLDYLLHRDDHAKMAEAVMELGAKNNVTLLCASLSLKDIAYLSSSAIRRECKPNESEVENFTRGF
LSSRVPWRCIEQVKEMCDIVAVDESTCDKAFSLQKRHRDFEDDLIIVAAQQSGANCVVTSDAELISHFPEYCRTPAEIVA
ALE
Download Length: 492 bp
>T159844 NZ_CP070157:2283358-2283735 [Escherichia coli]
ATGAAAACATTACCCGACACGCATGTACGGGAGGTATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGGTTACTGGACCAGCATTACAGCCTTACGCTGAATGACACACCGTTCGTGGATGAACGCGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTGAACTTTCTCGTGGAAAAATACGTACTGGTACGAACTGACCAGCCGGGATTC
AGCGCAGGAGCCTCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCCGGGCAACAGGTCTGATGACCCGCAG
CAACTACAGAACGGTAAATAACATTACCCGGGGGAAGCATCCGGAGGCGAAACAATGA
ATGAAAACATTACCCGACACGCATGTACGGGAGGTATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGGTTACTGGACCAGCATTACAGCCTTACGCTGAATGACACACCGTTCGTGGATGAACGCGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTGAACTTTCTCGTGGAAAAATACGTACTGGTACGAACTGACCAGCCGGGATTC
AGCGCAGGAGCCTCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCCGGGCAACAGGTCTGATGACCCGCAG
CAACTACAGAACGGTAAATAACATTACCCGGGGGAAGCATCCGGAGGCGAAACAATGA
Antitoxin
Download Length: 121 a.a. Molecular weight: 14004.05 Da Isoelectric Point: 5.0733
>AT159844 WP_011068030.1 NZ_CP054525:c2131135-2130773 [Bifidobacterium longum subsp. infantis]
MTMVQMNVRIDAKLKNEVEEVLKGKGVSVSDVIRSLWLYIADRKEVPALETTAEEQAREEEKQRKLKLIREGAGYVHKEL
VKAGLISEDTDLMEGLTYKQFRDKMYDEQLDTYYNMKRAD
MTMVQMNVRIDAKLKNEVEEVLKGKGVSVSDVIRSLWLYIADRKEVPALETTAEEQAREEEKQRKLKLIREGAGYVHKEL
VKAGLISEDTDLMEGLTYKQFRDKMYDEQLDTYYNMKRAD
Download Length: 363 bp
>AT159844 NZ_CP070157:2282900-2283268 [Escherichia coli]
GTGTCAGACACACTCTCCGGGACAACGCATCCCGATGACAATCACGACCATCCCTGGTGGGGACTACCCTGCACAGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTAACAGAGGCCGGT
TCAGAGATGCGGATGCGTACCCTCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGAAATTAATGCTCACCAGTGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCTGACACTCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA
GTGTCAGACACACTCTCCGGGACAACGCATCCCGATGACAATCACGACCATCCCTGGTGGGGACTACCCTGCACAGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTAACAGAGGCCGGT
TCAGAGATGCGGATGCGTACCCTCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGAAATTAATGCTCACCAGTGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCTGACACTCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7D5BU34 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S2W1N3 |