Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/PIN-RelB |
Location | 611729..612582 | Replicon | chromosome |
Accession | NZ_CP054519 | ||
Organism | Bifidobacterium longum subsp. infantis strain PI_010 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A7D5BU34 |
Locus tag | HUE69_RS02570 | Protein ID | WP_032745209.1 |
Coordinates | 612091..612582 (+) | Length | 164 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q8G4I4 |
Locus tag | HUE69_RS02565 | Protein ID | WP_011068030.1 |
Coordinates | 611729..612091 (+) | Length | 121 a.a. |
Genomic Context
Location: 608884..611583 (2700 bp)
Type: Others
Protein ID: WP_032745210.1
Type: Others
Protein ID: WP_032745210.1
Location: 611729..612091 (363 bp)
Type: Antitoxin
Protein ID: WP_011068030.1
Type: Antitoxin
Protein ID: WP_011068030.1
Location: 612091..612582 (492 bp)
Type: Toxin
Protein ID: WP_032745209.1
Type: Toxin
Protein ID: WP_032745209.1
Location: 615827..616729 (903 bp)
Type: Others
Protein ID: WP_032745207.1
Type: Others
Protein ID: WP_032745207.1
Location: 612643..614747 (2105 bp)
Type: Others
Protein ID: Protein_504
Type: Others
Protein ID: Protein_504
Location: 614836..615477 (642 bp)
Type: Others
Protein ID: WP_032745208.1
Type: Others
Protein ID: WP_032745208.1
Location: 615518..615658 (141 bp)
Type: Others
Protein ID: Protein_506
Type: Others
Protein ID: Protein_506
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HUE69_RS02560 (HUE69_02585) | 608884..611583 | + | 2700 | WP_032745210.1 | aconitate hydratase AcnA | - |
HUE69_RS02565 (HUE69_02590) | 611729..612091 | + | 363 | WP_011068030.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
HUE69_RS02570 (HUE69_02595) | 612091..612582 | + | 492 | WP_032745209.1 | PIN domain-containing protein | Toxin |
HUE69_RS02575 (HUE69_02600) | 612643..614747 | - | 2105 | Protein_504 | DUF262 domain-containing protein | - |
HUE69_RS02580 (HUE69_02605) | 614836..615477 | - | 642 | WP_032745208.1 | GNAT family N-acetyltransferase | - |
HUE69_RS02585 (HUE69_02610) | 615518..615658 | - | 141 | Protein_506 | LuxR C-terminal-related transcriptional regulator | - |
HUE69_RS02590 (HUE69_02615) | 615827..616729 | + | 903 | WP_032745207.1 | Bax inhibitor-1/YccA family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 18298.86 Da Isoelectric Point: 4.5590
>T159805 WP_032745209.1 NZ_CP054519:612091-612582 [Bifidobacterium longum subsp. infantis]
MTDVSMQRILLDTNVLLDYLLHRDDHAKMAEAVMELGAKNNVTLLCASLSLKDIAYLSSSAIRRECKPNESEVENFTRGF
LSSRVPWRCIEQVKEMCDIVAVDESTCDKAFSLQKRHRDFEDDLIIVAAQQSGANCVVTSDAELISHFPEYCRTPAEIVA
ALE
MTDVSMQRILLDTNVLLDYLLHRDDHAKMAEAVMELGAKNNVTLLCASLSLKDIAYLSSSAIRRECKPNESEVENFTRGF
LSSRVPWRCIEQVKEMCDIVAVDESTCDKAFSLQKRHRDFEDDLIIVAAQQSGANCVVTSDAELISHFPEYCRTPAEIVA
ALE
Download Length: 492 bp
>T159805 NZ_CP070148:c2506181-2506079 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 121 a.a. Molecular weight: 14004.05 Da Isoelectric Point: 5.0733
>AT159805 WP_011068030.1 NZ_CP054519:611729-612091 [Bifidobacterium longum subsp. infantis]
MTMVQMNVRIDAKLKNEVEEVLKGKGVSVSDVIRSLWLYIADRKEVPALETTAEEQAREEEKQRKLKLIREGAGYVHKEL
VKAGLISEDTDLMEGLTYKQFRDKMYDEQLDTYYNMKRAD
MTMVQMNVRIDAKLKNEVEEVLKGKGVSVSDVIRSLWLYIADRKEVPALETTAEEQAREEEKQRKLKLIREGAGYVHKEL
VKAGLISEDTDLMEGLTYKQFRDKMYDEQLDTYYNMKRAD
Download Length: 363 bp
>AT159805 NZ_CP070148:2506041-2506309 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7D5BU34 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S2W1N3 |