Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 137109..138064 Replicon chromosome
Accession NZ_CP054470
Organism Burkholderia gladioli strain CGB10

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag HUB32_RS36755 Protein ID WP_186289387.1
Coordinates 137531..138064 (+) Length 178 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag HUB32_RS36750 Protein ID WP_186289386.1
Coordinates 137109..137534 (+) Length 142 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUB32_RS36720 132217..132870 - 654 WP_036032694.1 AAA family ATPase -
HUB32_RS36725 133901..134143 + 243 WP_145757811.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
HUB32_RS36730 134140..134550 + 411 WP_145757807.1 type II toxin-antitoxin system VapC family toxin -
HUB32_RS36735 134966..135103 + 138 WP_186289384.1 hypothetical protein -
HUB32_RS36740 135416..135703 + 288 WP_145757805.1 hypothetical protein -
HUB32_RS36745 136166..136423 + 258 WP_186289385.1 hypothetical protein -
HUB32_RS36750 137109..137534 + 426 WP_186289386.1 DUF2384 domain-containing protein Antitoxin
HUB32_RS36755 137531..138064 + 534 WP_186289387.1 RES family NAD+ phosphorylase Toxin
HUB32_RS36760 139183..139425 + 243 WP_186289388.1 hypothetical protein -
HUB32_RS36765 139957..140295 + 339 WP_098183428.1 hypothetical protein -
HUB32_RS36770 140298..142133 + 1836 WP_186289389.1 site-specific integrase -
HUB32_RS36775 142409..142888 + 480 WP_013699966.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 87124..150257 63133


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(11-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 19048.64 Da        Isoelectric Point: 4.8723

>T159773 WP_186289387.1 NZ_CP054470:137531-138064 [Burkholderia gladioli]
MILTPLQDITAYRMHVPKWAVAPTSGAGAARAGGRANRIGTPALYLALEVATAVAEYQQLSPLLPPGTLVSYRVTATPVV
DFTGGFRADLWPPLWESFFCDWRRDWFNARIEPPSWVLGDEAIAAGAKGILFRSTQAAGGTNLVLFVDQLAEGDRLDVND
PAGALPRNQASWGEPTA

Download         Length: 534 bp

>T159773 NZ_CP070134:c2548285-2548178 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 142 a.a.        Molecular weight: 14965.81 Da        Isoelectric Point: 6.4664

>AT159773 WP_186289386.1 NZ_CP054470:137109-137534 [Burkholderia gladioli]
MSTLAATRAPTAPAGGPAPASFDAFLSALREPDTAAPVLSARRYVAALNIDLQTLADQAHVHRNTVARAPQSASVQQFLR
EAIRVIRAATDLSGDVQRALFWYRNEPLAVFDYQTAETLVSAGRADDVVRYVASLEAGAAG

Download         Length: 426 bp

>AT159773 NZ_CP070134:2548333-2548399 [Escherichia coli]
GGTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References