Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1831677..1833154 Replicon chromosome
Accession NZ_CP054424
Organism Rhodoferax sp. BAB1

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag HTY51_RS08750 Protein ID WP_174252382.1
Coordinates 1831677..1832552 (-) Length 292 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag HTY51_RS08755 Protein ID WP_174254218.1
Coordinates 1832549..1833154 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HTY51_RS08715 1827429..1829393 - 1965 WP_174254217.1 propionate--CoA ligase -
HTY51_RS08720 1829456..1829878 - 423 WP_174252378.1 DUF2784 domain-containing protein -
HTY51_RS08725 1829944..1830489 + 546 WP_174252379.1 NUDIX hydrolase -
HTY51_RS08730 1830626..1830802 + 177 WP_156404540.1 hypothetical protein -
HTY51_RS08735 1830872..1831138 + 267 WP_174252380.1 hypothetical protein -
HTY51_RS08745 1831500..1831670 + 171 WP_174252381.1 hypothetical protein -
HTY51_RS08750 1831677..1832552 - 876 WP_174252382.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
HTY51_RS08755 1832549..1833154 - 606 WP_174254218.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
HTY51_RS08760 1833339..1835255 - 1917 WP_174252383.1 FAD-dependent monooxygenase -
HTY51_RS08765 1835805..1836530 - 726 WP_174252384.1 hypothetical protein -
HTY51_RS08770 1836531..1837361 - 831 WP_174252385.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-261)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 292 a.a.        Molecular weight: 32048.08 Da        Isoelectric Point: 7.5176

>T159732 WP_174252382.1 NZ_CP054424:c1832552-1831677 [Rhodoferax sp. BAB1]
MSEGNGKNLAASVRARLLNLAKAERSDFNGVLLRYTLERLLYRLGQSDHAERFLLKGAMLFTVWYDMPHRPTRDVDLLGY
GPSDLPSVAQTFREVAAIAVADGVVFDPSSVSAEDIRKEAGYPGARIFINAELAGARLRAQVDIGFGDAVVPGPVAVKYP
VLLPDFPAPQLRAYPVHTVVAEKLHAIALLGMANTRMKDYLDLMVIFERESLELETLAQAIAATFARRGMPVPSTLPLGL
TDAFAEDDTRRTHWQAFLKKNDLAPVPLPEVLVRLRQHLQPALMQAARLQG

Download         Length: 876 bp

>T159732 NZ_CP070118:c35918-35640 [Escherichia coli]
ATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGATGGC
TGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGCCGCAACGGTCGTG
TGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTGTAT
ATCCTGCGAGTATTGCATACTGCACAGAAGTGGCCATAG

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22279.80 Da        Isoelectric Point: 9.7966

>AT159732 WP_174254218.1 NZ_CP054424:c1833154-1832549 [Rhodoferax sp. BAB1]
IHADTHPQRVLDLARRRGVLRPGDLEDVGAARVVLTRLMASGQLERVGRGLYRLPGAQVSAHETLATVAARVPQAVFCLL
TALQFHGLTTQLPRQVWIAMPRGSHVPRLDYPPLKMVQSSGEAFDEGIELHTRDQVPLRVYGVAKTVADCFKHRNKVGLD
VALEALREARAQNKATVDEIWHYAGICRVAQVMRPYLEALA

Download         Length: 606 bp

>AT159732 NZ_CP070118:c36187-35918 [Escherichia coli]
ATGGCACAGGTTAATATGAGTTTAAGAATCGACGCTGAACTGAAGGATGCTTTTATGGCCGCTGCAAAAAGCATGGACCG
TAATGGCTCCCAGTTAATCCGGGATTTTATGCGCCAGACCGTTGAACGGCAGCATAATACCTGGTTCCGTGACCAGGTTG
CGGCAGGACGTCAGCAACTCGAGCACGGCGATGTGCTTCCCCATGACATGGTCGAATCCTCTGCTGCAGCATGGCGGGAT
GAAATGAGCAGGAAGGTTGCCGGTAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References