Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1880767..1880912 Replicon chromosome
Accession NZ_CP054406
Organism Klebsiella pneumoniae strain KCJ3K293

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1880803..1880905 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1880767..1880912 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOH49_RS10750 (FOH49_010770) 1875897..1877957 + 2061 WP_004151449.1 oligopeptidase B -
FOH49_RS10755 (FOH49_010775) 1877961..1878620 - 660 WP_002911407.1 exodeoxyribonuclease X -
FOH49_RS10760 (FOH49_010780) 1878699..1878929 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FOH49_RS10765 (FOH49_010785) 1879042..1879416 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FOH49_RS10770 (FOH49_010790) 1879420..1880289 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
FOH49_RS10775 (FOH49_010795) 1880306..1880644 + 339 WP_002911404.1 YebY family protein -
- 1880767..1880912 - 146 - - Antitoxin
- 1880803..1880905 + 103 - - Toxin
FOH49_RS10780 (FOH49_010800) 1881281..1881424 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FOH49_RS10785 (FOH49_010805) 1881529..1882497 - 969 WP_004151446.1 VirK/YbjX family protein -
FOH49_RS10790 (FOH49_010810) 1882654..1883307 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
FOH49_RS10795 (FOH49_010815) 1883304..1883495 - 192 WP_002911395.1 YebW family protein -
FOH49_RS10800 (FOH49_010820) 1883593..1883832 - 240 WP_002911393.1 YebV family protein -
FOH49_RS10805 (FOH49_010825) 1883948..1885381 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T159647 NZ_CP054406:1880803-1880905 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT159647 NZ_CP054406:c1880912-1880767 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References