Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1880768..1880913 Replicon chromosome
Accession NZ_CP054400
Organism Klebsiella pneumoniae strain KCJ3K307

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1880804..1880906 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1880768..1880913 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOH51_RS10750 (FOH51_010740) 1875898..1877958 + 2061 WP_004151449.1 oligopeptidase B -
FOH51_RS10755 (FOH51_010745) 1877962..1878621 - 660 WP_002911407.1 exodeoxyribonuclease X -
FOH51_RS10760 (FOH51_010750) 1878700..1878930 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FOH51_RS10765 (FOH51_010755) 1879043..1879417 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FOH51_RS10770 (FOH51_010760) 1879421..1880290 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
FOH51_RS10775 (FOH51_010765) 1880307..1880645 + 339 WP_002911404.1 YebY family protein -
- 1880768..1880913 - 146 - - Antitoxin
- 1880804..1880906 + 103 - - Toxin
FOH51_RS10780 (FOH51_010770) 1881282..1881425 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FOH51_RS10785 (FOH51_010775) 1881530..1882498 - 969 WP_004151446.1 VirK/YbjX family protein -
FOH51_RS10790 (FOH51_010780) 1882655..1883308 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
FOH51_RS10795 (FOH51_010785) 1883305..1883496 - 192 WP_002911395.1 YebW family protein -
FOH51_RS10800 (FOH51_010790) 1883594..1883833 - 240 WP_002911393.1 YebV family protein -
FOH51_RS10805 (FOH51_010795) 1883949..1885382 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T159603 NZ_CP054400:1880804-1880906 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT159603 NZ_CP054400:c1880913-1880768 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References