159398

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 63149..63545 Replicon chromosome
Accession NZ_CP054306
Organism Synechocystis sp. PCC 7338

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HTZ78_RS17960 Protein ID WP_249213946.1
Coordinates 63149..63259 (-) Length 37 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HTZ78_RS00355 Protein ID WP_212717911.1
Coordinates 63327..63545 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HTZ78_RS00315 (HTZ78_00315) 59128..59496 - 369 WP_212717903.1 photosystem II reaction center protein Psb28 -
HTZ78_RS00320 (HTZ78_00320) 59751..60227 + 477 WP_212717904.1 DUF1499 domain-containing protein -
HTZ78_RS00325 (HTZ78_00325) 60243..60662 - 420 WP_194014014.1 Fur family transcriptional regulator -
HTZ78_RS00330 (HTZ78_00330) 60975..61544 + 570 WP_212717905.1 peroxiredoxin -
HTZ78_RS00335 (HTZ78_00335) 61786..62335 - 550 Protein_63 transposase -
HTZ78_RS00340 (HTZ78_00340) 62325..62813 - 489 WP_212717907.1 IS630 transposase-related protein -
HTZ78_RS00345 (HTZ78_00345) 62791..63024 - 234 WP_212717909.1 IS630 transposase-related protein -
HTZ78_RS17960 63149..63259 - 111 WP_249213946.1 putative toxin-antitoxin system toxin component, PIN family Toxin
HTZ78_RS00355 (HTZ78_00355) 63327..63545 - 219 WP_212717911.1 hypothetical protein Antitoxin
HTZ78_RS00360 (HTZ78_00360) 63825..65102 + 1278 WP_212717913.1 adenosylhomocysteinase -
HTZ78_RS00365 (HTZ78_00365) 65299..67581 - 2283 WP_212717915.1 RelA/SpoT family protein -
HTZ78_RS00370 (HTZ78_00370) 67956..68339 + 384 WP_212717917.1 heterocyst frequency control protein PatD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 62325..73413 11088


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN family, putative toxin-antitoxin system toxin component

(1-36)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 37 a.a.        Molecular weight: 4345.10 Da        Isoelectric Point: 7.0052

>T159398 WP_249213946.1 NZ_CP054306:c63259-63149 [Synechocystis sp. PCC 7338]
MNQTIIDNRVAILFSEDLFAELMEVLHRPKFKKYFS

Download         Length: 111 bp

>T159398 NZ_CP070041:1148764-1149042 [Escherichia coli]
ATGTTACCCGTGTTATGGCTTGAAAGCGCAGATACCGACCTAGATGATATAACTAGTTATATTGCTCGTTTCGACATAGA
TGCGGCTGAACGCTTATGGCAGCGATTAAGGGGTTGTGTGCTGCCGTTATCCGAACATCCGTATTTATACCCACCAAGCG
ACAGAGTACCTGGCTTGCGTGAGATTGTAGCCCACCCTAACTATATAATTCTATACCGCGTAACAACATCAAGCGTTGAA
GTAGTAAACGTGATCCACGCAAGACGCCAGTTTCCCTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8513.85 Da        Isoelectric Point: 5.1423

>AT159398 WP_212717911.1 NZ_CP054306:c63545-63327 [Synechocystis sp. PCC 7338]
MKSLSLLDFLELKNIIAQCNLEEKLELLELLKKDTFATRFNKFLDSVKTDELTLEDITREVEAVRQANYHKR

Download         Length: 219 bp

>AT159398 NZ_CP070041:1148571-1148762 [Escherichia coli]
ATGAATAGAGCCCTTTCACCAATGGTTTCTGAATTTGAAACCATTGAACAAGAAAACAGTTACAACGAATGGCTGCGTGC
GAAAGTAGCAACGAGCCTTGCAGATCCGCGCCCAGCAATTCCCCATGACGAAGTTGAGCGCAGAATGGCAGAACGCTTTG
CTAAGATGCGTAAGGAACGGAGCAAGCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References