159376

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2700427..2700986 Replicon chromosome
Accession NZ_CP054301
Organism Marinomonas primoryensis strain MPKMM3633

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MP3633_RS12485 Protein ID WP_176335790.1
Coordinates 2700708..2700986 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MP3633_RS12480 Protein ID WP_176335789.1
Coordinates 2700427..2700711 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MP3633_RS12445 2695873..2696067 + 195 WP_176333945.1 hypothetical protein -
MP3633_RS12450 2696098..2696544 - 447 WP_176335785.1 thioredoxin TrxC -
MP3633_RS12455 2696733..2697422 - 690 WP_176335786.1 hypothetical protein -
MP3633_RS12460 2697883..2698467 - 585 WP_176336803.1 DUF938 domain-containing protein -
MP3633_RS12465 2698613..2698948 - 336 WP_176335787.1 AzlD domain-containing protein -
MP3633_RS12470 2698951..2699673 - 723 WP_176335788.1 AzlC family ABC transporter permease -
MP3633_RS12475 2699670..2700230 - 561 WP_176336804.1 helix-turn-helix transcriptional regulator -
MP3633_RS12480 2700427..2700711 + 285 WP_176335789.1 damage-inducible protein J Antitoxin
MP3633_RS12485 2700708..2700986 + 279 WP_176335790.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MP3633_RS12490 2701064..2701459 - 396 WP_176335791.1 cupin domain-containing protein -
MP3633_RS12495 2701833..2702306 - 474 WP_176335792.1 hypothetical protein -
MP3633_RS12500 2702392..2703567 - 1176 WP_176336805.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11046.91 Da        Isoelectric Point: 4.8550

>T159376 WP_176335790.1 NZ_CP054301:2700708-2700986 [Marinomonas primoryensis]
MIFWEEESLNDREKIFDFLFDFNPSVAEKTDQIIEAKVENLLIQPLMGVQRHIFRGRVLIIPEISMIVSYWVDGEIIRIM
RVLHQKQKFPQE

Download         Length: 279 bp

>T159376 NZ_CP070027:c47813-47433 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTGATAGCGCTTCATGATGCGAATATAAGCCGCTACGGCGGCCTGCCGGGAATGTC
AGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGTTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACCGTAGGGGCTGCGACCGG
AGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTTCCGCGGAGTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10998.42 Da        Isoelectric Point: 7.1698

>AT159376 WP_176335789.1 NZ_CP054301:2700427-2700711 [Marinomonas primoryensis]
MDTRIQFRIDEETKRLAQLMAESQGRTLSDACRELTEGLAEEQRKSMTHDLWLTEQINAAFDKFDSGKSIFIEHDKAKAQ
MEARKNKIRNRDKP

Download         Length: 285 bp

>AT159376 NZ_CP070027:c48034-47813 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGCGGCAACCTTTCTGAAGTGCTCAACAATGTTGAAGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGTGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTCGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References