Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) sdenTA/AbiEii(toxin)
Location 2413387..2414803 Replicon chromosome
Accession NZ_CP054301
Organism Marinomonas primoryensis strain MPKMM3633

Toxin (Protein)


Gene name sdenT Uniprot ID -
Locus tag MP3633_RS11190 Protein ID WP_176335607.1
Coordinates 2413913..2414803 (+) Length 297 a.a.

Antitoxin (Protein)


Gene name sdenA Uniprot ID -
Locus tag MP3633_RS11185 Protein ID WP_176335606.1
Coordinates 2413387..2413911 (+) Length 175 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MP3633_RS11160 2408894..2409091 - 198 WP_024023255.1 4-oxalocrotonate tautomerase family protein -
MP3633_RS11165 2409221..2410144 - 924 WP_176335603.1 LysR family transcriptional regulator -
MP3633_RS11170 2410224..2411108 - 885 WP_176335604.1 LysR family transcriptional regulator -
MP3633_RS11175 2411208..2411831 + 624 WP_176336790.1 NAD(P)-binding domain-containing protein -
MP3633_RS11180 2412005..2413009 + 1005 WP_176335605.1 alpha/beta hydrolase -
MP3633_RS11185 2413387..2413911 + 525 WP_176335606.1 hypothetical protein Antitoxin
MP3633_RS11190 2413913..2414803 + 891 WP_176335607.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MP3633_RS11220 2416616..2417275 + 660 WP_176335608.1 peptide-methionine (S)-S-oxide reductase MsrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(36-265)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 297 a.a.        Molecular weight: 34323.54 Da        Isoelectric Point: 6.2586

>T159374 WP_176335607.1 NZ_CP054301:2413913-2414803 [Marinomonas primoryensis]
MLKEVIKQIINTNPEYAGITPVIEKEILHHDIMAVMVKQGVMQSLTFIGGTSLRLCHNSSRLSEDLDFNGGHDFKPADFD
GLEVEIQKYIQKKYETQIWVNKPSQDKQGDTSSWQISIEKEANRPDLPRQKMHIDVCAIPSFDIERRPLINHYDVVVPTE
GLLIPVQSLEETLADKFIALAYRARRIKPRDVWDILWIKQRGIDVSIELINKKLAARGKTKTNFIETLTLQVEKLLNEEE
VKADFNNEMSRFIPSQIKERTIDNPEYWQYVQLEIKSMTDPILKPNLQTKKFDMGF

Download         Length: 891 bp

>T159374 NZ_CP070026:c3924449-3924198 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 175 a.a.        Molecular weight: 19340.40 Da        Isoelectric Point: 9.9254

>AT159374 WP_176335606.1 NZ_CP054301:2413387-2413911 [Marinomonas primoryensis]
MRKKEKLLSVLSHATKAGGGVHTATEIAFMLGEKHTPSFTKFLTDCVQKGVLRRVATGIFESTITPPDGSTAIYKIVNKL
RGDVLNYISLESQLSYTGDISQIVMDRLTVMTKGRSGIFSTPYGVIEFTHTKKTIESIAPNIYFDSDIKMYRARTSQAIV
DLKNCNRNLQMLEA

Download         Length: 525 bp

>AT159374 NZ_CP070026:c3924201-3923947 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References