Detailed information of TA system TA159374

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 2413387..2414803
• Replicon: chromosome
• Accession: NZ_CP054301
• Organism: Marinomonas primoryensis strain MPKMM3633

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: MP3633_RS11190
• Protein ID: WP_176335607.1
• Coordinates: 2413913..2414803 (+)
• Length: 297 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: MP3633_RS11185
• Protein ID: WP_176335606.1
• Coordinates: 2413387..2413911 (+)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MP3633_RS11160	2408894..2409091	-	198	WP_024023255.1	4-oxalocrotonate tautomerase family protein	-
MP3633_RS11165	2409221..2410144	-	924	WP_176335603.1	LysR family transcriptional regulator	-
MP3633_RS11170	2410224..2411108	-	885	WP_176335604.1	LysR family transcriptional regulator	-
MP3633_RS11175	2411208..2411831	+	624	WP_176336790.1	NAD(P)-binding domain-containing protein	-
MP3633_RS11180	2412005..2413009	+	1005	WP_176335605.1	alpha/beta hydrolase	-
MP3633_RS11185	2413387..2413911	+	525	WP_176335606.1	hypothetical protein	Antitoxin
MP3633_RS11190	2413913..2414803	+	891	WP_176335607.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
MP3633_RS11220	2416616..2417275	+	660	WP_176335608.1	peptide-methionine (S)-S-oxide reductase MsrA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-265)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 297 a.a.
• Molecular weight: 34323.54 Da
• Isoelectric Point: 6.2586

>T159374 WP_176335607.1 NZ_CP054301:2413913-2414803 [Marinomonas primoryensis]
MLKEVIKQIINTNPEYAGITPVIEKEILHHDIMAVMVKQGVMQSLTFIGGTSLRLCHNSSRLSEDLDFNGGHDFKPADFD
GLEVEIQKYIQKKYETQIWVNKPSQDKQGDTSSWQISIEKEANRPDLPRQKMHIDVCAIPSFDIERRPLINHYDVVVPTE
GLLIPVQSLEETLADKFIALAYRARRIKPRDVWDILWIKQRGIDVSIELINKKLAARGKTKTNFIETLTLQVEKLLNEEE
VKADFNNEMSRFIPSQIKERTIDNPEYWQYVQLEIKSMTDPILKPNLQTKKFDMGF

Nucleotide

• Length: 891 bp

>T159374 NZ_CP070026:c3924449-3924198 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19340.40 Da
• Isoelectric Point: 9.9254

>AT159374 WP_176335606.1 NZ_CP054301:2413387-2413911 [Marinomonas primoryensis]
MRKKEKLLSVLSHATKAGGGVHTATEIAFMLGEKHTPSFTKFLTDCVQKGVLRRVATGIFESTITPPDGSTAIYKIVNKL
RGDVLNYISLESQLSYTGDISQIVMDRLTVMTKGRSGIFSTPYGVIEFTHTKKTIESIAPNIYFDSDIKMYRARTSQAIV
DLKNCNRNLQMLEA

Nucleotide

• Length: 525 bp

>AT159374 NZ_CP070026:c3924201-3923947 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA