Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2553146..2553291 Replicon chromosome
Accession NZ_CP054285
Organism Klebsiella pneumoniae strain IDR1800050501-01-02

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2553182..2553284 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2553146..2553291 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HS091_RS12235 2548276..2550336 + 2061 WP_004151449.1 oligopeptidase B -
HS091_RS12240 2550340..2550999 - 660 WP_002911407.1 exodeoxyribonuclease X -
HS091_RS12245 2551078..2551308 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HS091_RS12250 2551421..2551795 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HS091_RS12255 2551799..2552668 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HS091_RS12260 2552685..2553023 + 339 WP_004189269.1 YebY family protein -
- 2553146..2553291 - 146 - - Antitoxin
- 2553182..2553284 + 103 - - Toxin
HS091_RS12265 2553658..2553801 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HS091_RS12270 2553906..2554874 - 969 WP_004151446.1 VirK/YbjX family protein -
HS091_RS12275 2555031..2555684 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
HS091_RS12280 2555681..2555872 - 192 WP_002911395.1 YebW family protein -
HS091_RS12285 2555970..2556209 - 240 WP_002911393.1 YebV family protein -
HS091_RS12290 2556325..2557759 - 1435 Protein_2380 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T159338 NZ_CP054285:2553182-2553284 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT159338 NZ_CP054285:c2553291-2553146 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References