Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1992060..1992205 | Replicon | chromosome |
| Accession | NZ_CP054268 | ||
| Organism | Klebsiella pneumoniae strain 39427 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1992096..1992198 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1992060..1992205 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HPS02_RS11610 | 1987190..1989250 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| HPS02_RS11615 | 1989254..1989913 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HPS02_RS11620 | 1989992..1990222 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HPS02_RS11625 | 1990335..1990709 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| HPS02_RS11630 | 1990713..1991582 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| HPS02_RS11635 | 1991599..1991937 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1992060..1992205 | - | 146 | - | - | Antitoxin |
| - | 1992096..1992198 | + | 103 | - | - | Toxin |
| HPS02_RS11640 | 1992573..1992716 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| HPS02_RS11645 | 1992821..1993789 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| HPS02_RS11650 | 1993946..1994599 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| HPS02_RS11655 | 1994596..1994787 | - | 192 | WP_002911395.1 | YebW family protein | - |
| HPS02_RS11660 | 1994885..1995124 | - | 240 | WP_002911393.1 | YebV family protein | - |
| HPS02_RS11665 | 1995240..1996673 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T159244 NZ_CP054268:1992096-1992198 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT159244 NZ_CP054268:c1992205-1992060 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT