Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1992060..1992205 Replicon chromosome
Accession NZ_CP054268
Organism Klebsiella pneumoniae strain 39427

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1992096..1992198 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1992060..1992205 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPS02_RS11610 1987190..1989250 + 2061 WP_004151449.1 oligopeptidase B -
HPS02_RS11615 1989254..1989913 - 660 WP_002911407.1 exodeoxyribonuclease X -
HPS02_RS11620 1989992..1990222 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HPS02_RS11625 1990335..1990709 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HPS02_RS11630 1990713..1991582 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HPS02_RS11635 1991599..1991937 + 339 WP_002911404.1 YebY family protein -
- 1992060..1992205 - 146 - - Antitoxin
- 1992096..1992198 + 103 - - Toxin
HPS02_RS11640 1992573..1992716 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HPS02_RS11645 1992821..1993789 - 969 WP_004151446.1 VirK/YbjX family protein -
HPS02_RS11650 1993946..1994599 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
HPS02_RS11655 1994596..1994787 - 192 WP_002911395.1 YebW family protein -
HPS02_RS11660 1994885..1995124 - 240 WP_002911393.1 YebV family protein -
HPS02_RS11665 1995240..1996673 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T159244 NZ_CP054268:1992096-1992198 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT159244 NZ_CP054268:c1992205-1992060 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References