Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 770736..771211 Replicon chromosome
Accession NZ_CP054258
Organism Treponema socranskii subsp. buccale strain ATCC 35534

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HRI97_RS03420 Protein ID WP_253726572.1
Coordinates 770966..771211 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag HRI97_RS03415 Protein ID WP_253726570.1
Coordinates 770736..770969 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRI97_RS03395 (HRI97_03400) 766168..766635 - 468 WP_253726562.1 hypothetical protein -
HRI97_RS03400 (HRI97_03405) 766632..767723 - 1092 WP_253726564.1 RHS repeat-associated core domain-containing protein -
HRI97_RS03405 (HRI97_03410) 768053..769051 - 999 WP_253726566.1 SPOR domain-containing protein -
HRI97_RS03410 (HRI97_03415) 769250..770074 - 825 WP_253726568.1 DeoR/GlpR family DNA-binding transcription regulator -
HRI97_RS03415 (HRI97_03420) 770736..770969 + 234 WP_253726570.1 hypothetical protein Antitoxin
HRI97_RS03420 (HRI97_03425) 770966..771211 + 246 WP_253726572.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HRI97_RS03425 (HRI97_03430) 771318..771569 + 252 WP_253726574.1 hypothetical protein -
HRI97_RS03430 (HRI97_03435) 771569..771955 + 387 WP_253726576.1 hypothetical protein -
HRI97_RS03435 (HRI97_03440) 772217..772600 + 384 WP_253726578.1 hypothetical protein -
HRI97_RS03440 (HRI97_03445) 772600..773202 + 603 WP_253726580.1 hypothetical protein -
HRI97_RS03445 (HRI97_03450) 773683..774669 - 987 WP_253726582.1 5-dehydro-2-deoxygluconokinase -
HRI97_RS03450 (HRI97_03455) 774670..775485 - 816 WP_253726584.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 766632..778518 11886


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-71)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9370.15 Da        Isoelectric Point: 10.1751

>T159225 WP_253726572.1 NZ_CP054258:770966-771211 [Treponema socranskii subsp. buccale]
MTVVFAEKAKKEFLKLDKPVQKQIQIFIVKLQNMEDPRVSGKALGGNLAGMWRYRVGDYRLVCEIENDKILINNLFFAKP
L

Download         Length: 246 bp

>T159225 NZ_CP069980:c4248175-4248068 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8786.05 Da        Isoelectric Point: 4.5702

>AT159225 WP_253726570.1 NZ_CP054258:770736-770969 [Treponema socranskii subsp. buccale]
MALTVTATFRTKPELKSRIELLAKATRRSTSFYYNLLLEDYLDDLEDIYLSEQILADIRSGKQKTIPAEEVFAEAGL

Download         Length: 234 bp

>AT159225 NZ_CP069980:4248228-4248289 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References