Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2484234..2484502 Replicon chromosome
Accession NZ_CP054236
Organism Escherichia coli strain EcPF5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2484362..2484464 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2484234..2484502 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HR070_RS11635 2480786..2481448 - 663 WP_000944256.1 exodeoxyribonuclease X -
HR070_RS11640 2481472..2482128 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
HR070_RS11645 2482231..2482461 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HR070_RS11650 2482600..2482974 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HR070_RS11655 2482978..2483850 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
HR070_RS11660 2483863..2484204 + 342 WP_000984819.1 YebY family protein -
- 2484234..2484502 - 269 - - Antitoxin
- 2484362..2484464 + 103 - - Toxin
HR070_RS11665 2484599..2485255 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
HR070_RS11670 2485256..2485447 - 192 WP_001317886.1 YebW family protein -
HR070_RS11675 2485552..2485788 - 237 WP_001295499.1 DUF1480 family protein -
HR070_RS11680 2485906..2487345 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T159169 NZ_CP054236:2484362-2484464 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT159169 NZ_CP054236:c2484502-2484234 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References