Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2294087..2294355 Replicon chromosome
Accession NZ_CP054230
Organism Escherichia coli strain EcPF14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2294215..2294317 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2294087..2294355 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HR072_RS10745 2290639..2291301 - 663 WP_000944256.1 exodeoxyribonuclease X -
HR072_RS10750 2291325..2291981 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
HR072_RS10755 2292084..2292314 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HR072_RS10760 2292453..2292827 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HR072_RS10765 2292831..2293703 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
HR072_RS10770 2293716..2294057 + 342 WP_000984819.1 YebY family protein -
- 2294087..2294355 - 269 - - Antitoxin
- 2294215..2294317 + 103 - - Toxin
HR072_RS10775 2294452..2295108 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
HR072_RS10780 2295109..2295300 - 192 WP_001317886.1 YebW family protein -
HR072_RS10785 2295405..2295641 - 237 WP_001295499.1 DUF1480 family protein -
HR072_RS10790 2295759..2297198 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T159100 NZ_CP054230:2294215-2294317 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT159100 NZ_CP054230:c2294355-2294087 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References