Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012692..2012963 Replicon chromosome
Accession NZ_CP054224
Organism Escherichia coli strain EcPF16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012822..2012925 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012692..2012963 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HR074_RS09650 2009247..2009909 - 663 WP_000944256.1 exodeoxyribonuclease X -
HR074_RS09655 2009933..2010589 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
HR074_RS09660 2010691..2010921 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HR074_RS09665 2011060..2011434 + 375 WP_000168738.1 CopC domain-containing protein YobA -
HR074_RS09670 2011438..2012310 + 873 WP_000879286.1 copper homeostasis membrane protein CopD -
HR074_RS09675 2012323..2012664 + 342 WP_000976472.1 YebY family protein -
- 2012692..2012963 - 272 - - Antitoxin
- 2012822..2012925 + 104 - - Toxin
HR074_RS09680 2013060..2013716 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
HR074_RS09685 2013717..2013908 - 192 WP_001313035.1 YebW family protein -
HR074_RS09690 2014013..2014249 - 237 WP_001295499.1 DUF1480 family protein -
HR074_RS09695 2014367..2015806 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T159041 NZ_CP054224:2012822-2012925 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT159041 NZ_CP054224:c2012963-2012692 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References